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Article
Publication date: 4 November 2022

Mahenderan Appukutty, Sangeetha Shyam, Zi Ying Choo, Seok Shin Tan, Hueh Zan Megan Chong and Alston Choong

The present randomised controlled trial aimed to assess the effects of 8-week supplementation of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) on the n-3 index and…

Abstract

Purpose

The present randomised controlled trial aimed to assess the effects of 8-week supplementation of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) on the n-3 index and performance of professional male football players.

Design/methodology/approach

A total of 27 professional male football players were randomly assigned into 2 groups: placebo (n = 14) and n-3 LCPUFA (n = 13). n-3 LCPUFA supplements containing 1.5 g eicosapentaenoic acid (EPA) and 600 mg docosahexaenoic acid (DHA) were administered as 6 capsules (four in the morning and two in the evening, 30 min after a meal). Anthropometry, body composition, dried-blood spot n-3 LCPUFA levels, exercise performance and dietary intake of football players were measured at week 0, week 4 and week 8.

Findings

n-3 LCPUFA supplementation improved blood levels of EPA and DHA levels, omega-3 index vs placebo (p time*group = 0.010, 0.041 and 0.018, respectively). n-3 LCPUFA supplemented group had significantly higher aerobic capacity than placebo participants, at week 8 (p group = 0.021).

Originality/value

This study shows the effect of n-3 LCPUFA supplementation in Malaysian professional male football players involved in team sports having low dietary intakes of n-3 LCPUFA.

Details

British Food Journal, vol. 125 no. 6
Type: Research Article
ISSN: 0007-070X

Keywords

Article
Publication date: 19 July 2011

Chong Hueh Zan, Asmah Rahmat, Abdah, Akim, Norjahan Banu Mohd. Alitheen, Fauziah Othman and Gwendoline Ee Cheng Lian

The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves…

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Abstract

Purpose

The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines.

Design/methodology/approach

Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts (0‐100 μg/ml) using 72‐h MTT assay.

Findings

Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma), HT‐29 (colon carcinoma), MDA‐MB‐231 (non‐hormone‐dependent breast cancer), MCF‐7 (hormone‐dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC50) were obtained for MDA‐MB‐231, HepG2, HT‐29. Extracts within the concentrations of 10‐100 μg/ml were found not to be effective against proliferation of MCF‐7 and HeLa.

Originality/value

The paper shows how culinary plants – daun pandan, turmeric leaves and kantan flower displayed selective cytotoxic effects towards liver, colon and breast cancer in vitro.

Details

Nutrition & Food Science, vol. 41 no. 4
Type: Research Article
ISSN: 0034-6659

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