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1 – 10 of 820Chengkuan Zeng, Shiming Chen and Chongjun Yan
This study addresses the production optimization of a cellular manufacturing system (CMS) in magnetic production enterprises. Magnetic products and raw materials are more critical…
Abstract
Purpose
This study addresses the production optimization of a cellular manufacturing system (CMS) in magnetic production enterprises. Magnetic products and raw materials are more critical to transport than general products because the attraction or repulsion between magnetic poles can easily cause traffic jams. This study needs to address a method to promote the scheduling efficiency of the problem.
Design/methodology/approach
To address this problem, this study formulated a mixed-integer linear programming (MILP) model to describe the problem and proposed an auction and negotiation-based approach with a local search to solve it. Auction- and negotiation-based approaches can obtain feasible and high-quality solutions. A local search operator was proposed to optimize the feasible solutions using an improved conjunctive graph model.
Findings
Verification tests were performed on a series of numerical examples. The results demonstrated that the proposed auction and negotiation-based approach with a local search operator is better than existing solution methods for the problem identified. Statistical analysis of the experiment results using the Statistical Package for the Social Sciences (SPSS) software demonstrated that the proposed approach is efficient, stable and suitable for solving large-scale numerical instances.
Originality/value
An improved auction and negotiation-based approach was proposed; The conjunctive graph model was also improved to describe the problem of CMS with traffic jam constraint and build the local search operator; The authors’ proposed approach can get better solution than the existing algorithms by testing benchmark instances and real-world instances from enterprises.
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Amin Reihani, Fatemeh Shaki and Ala Azari
Acrylamide (AA) is predominantly used as a synthetic substance within various industries. However, AA is also recognized as a carcinogen. Zinc oxide nanoparticles (ZnO-NPs) are…
Abstract
Purpose
Acrylamide (AA) is predominantly used as a synthetic substance within various industries. However, AA is also recognized as a carcinogen. Zinc oxide nanoparticles (ZnO-NPs) are becoming increasingly attractive as medical agents. However, to the knowledge, the effects of ZnO-NPs on preventing cytotoxicity with AA have not been reported. Therefore, this study aims to determine the protective effects of ZnO-NPs against the cytotoxicity caused by AA.
Design/methodology/approach
MTT assay was used to determine the cytotoxicity. Reactive oxygen species (ROS) formation, carbonyl protein, malondialdehyde (MDA) and glutathione (GSH) were measured and analyzed statistically.
Findings
The findings observed that the presence of 200 µM AA led to a substantial reduction in cell viability (p < 0.001). However, ZnO-NPs restored cell viability at 50 and 100 µM concentrations (p = 0.0121 and p = 0.0011, respectively). The levels of ROS were significantly reduced (p = 0.001 and p = < 0.001) to 518 ± 47.57 and 364 ± 47.79, respectively, compared to the AA group. The levels of GSH were significantly increased (p = 0.004 and p = 0.002) to 16.9 ± 1.3 and 17.6 ± 0.5, respectively, compared to the AA group. The levels of MDA were significantly decreased (p = 0.005, p < 0.001 and p < 0.001) when compared to the AA group, as were the levels of carbonyl protein (p = 0.009 and p < 0.002) in comparison to the AA group.
Originality/value
In summary, the outcomes of this research indicate that ZnO-NPs played a role in inhibiting AA-induced oxidative stress and cytotoxicity.
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Bhanu Prakash Saripalli, Gagan Singh and Sonika Singh
Estimation of solar cell parameters, mathematical modeling and the actual performance analysis of photovoltaic (PV) cells at various ecological conditions are very important in…
Abstract
Purpose
Estimation of solar cell parameters, mathematical modeling and the actual performance analysis of photovoltaic (PV) cells at various ecological conditions are very important in the design and analysis of maximum power point trackers and power converters. This study aims to propose the analysis and modeling of a simplified three-diode model based on the manufacturer’s performance data.
Design/methodology/approach
A novel technique is presented to evaluate the PV cell constraints and simplify the existing equation using analytical and iterative methods. To examine the current equation, this study focuses on three crucial operational points: open circuit, short circuit and maximum operating points. The number of parameters needed to estimate these built-in models is decreased from nine to five by an effective iteration method, considerably reducing computational requirements.
Findings
The proposed model, in contrast to the previous complex nine-parameter three-diode model, simplifies the modeling and analysis process by requiring only five parameters. To ensure the reliability and accuracy of this proposed model, its results were carefully compared with datasheet values under standard test conditions (STC). This model was implemented using MATLAB/Simulink and validated using a polycrystalline solar cell under STC conditions.
Originality/value
The proposed three-diode model clearly outperforms the earlier existing two-diode model in terms of accuracy and performance, especially in lower irradiance settings, according to the results and comparison analysis.
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Halla Falih Bakheit, Sebastien Taurin, Elwaleed Mohamed Elamin and Moiz Bakhiet
Monocytes are a leukocytes’ subset that plays an important role in immunity. Protein kinase B (AKT) is involved in monocytes' survival, proliferation and differentiation. Using…
Abstract
Purpose
Monocytes are a leukocytes’ subset that plays an important role in immunity. Protein kinase B (AKT) is involved in monocytes' survival, proliferation and differentiation. Using phorbol 12-myristate 13-acetate (PMA) as an inducer for cell line U937 differentiation into macrophage-like cells may be used as a model for cancer cell therapy or other biomedical research studies. The authors investigated the Akt1 signaling pathway's involvement with PMA as a differentiating agent and survival in the U937 cell line.
Design/methodology/approach
PMA was utilized to stimulate the differentiation of the U937 cell line into macrophage-like cells at a concentration of 10 nM. Akt1-phosphorylated Serine 473, Bad-phosphorylated Serine 136 and Caspase9-phosphorylated Serine 196 were tested by flow cytometry for the involvement of the Akt1 signaling pathway during differentiation in addition to the expression of CD14, CD206 and CD83. DNA cell cycle variation analysis was done using PI staining and cell viability and apoptosis detection using Annexin V and PI flow cytometry.
Findings
There was a decrease in phosphorylated Akt1 and Bad activation and an increase in Caspase9 activation, with an increase in surface markers CD14, CD206 and CD83 acquired by PMA-differentiated cells. DNA cell cycle analysis revealed cell accumulation in the G2/M phase and fewer cells in the S phase of PMA-induced U937. Apoptosis induction for Ly294002 or Wortmannin-inhibited cells and part of PMA-induced cells were detected.
Originality/value
These results may be used to create a model for biomedical research studies and advance the understanding of the mechanism involving differentiation of the U937 cell line.
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Vikrant Sharma and Dheeraj Nimawat
The purpose of this article is to conduct a bibliometric analysis of the cellular manufacturing system (CMS) literature published from 1982–2021 to identify key issues and trends…
Abstract
Purpose
The purpose of this article is to conduct a bibliometric analysis of the cellular manufacturing system (CMS) literature published from 1982–2021 to identify key issues and trends for the future.
Design/methodology/approach
A six-stage methodology is used to conduct a literature review, which includes: (1) article collection; (2) inclusion/exclusion criteria; (3) reviewing the articles; (4) analyzing the articles; (5) framework development; and (6) future research directions. A total of 936 CMS-specific articles are reviewed. This paper made use of three software tools: the R package, VOSviewer and SciMAT.
Findings
According to the findings, the majority of CM researchers focused on cell formation and design. The USA, Iran and India are the top three leading publishers. Additionally, the gap and future direction of CM are discussed.
Originality/value
To the best of the authors' knowledge, the current study is the first attempt to investigate CMS evaluation through bibliometric and thematic analysis and provides a decisional framework as well as steps for CMS adoption. For individuals who are interested in understanding more about CMS and its evolution, this paper offers a starting point.
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Naseer Khan, Zeeshan Gohar, Faisal Khan and Faisal Mehmood
This study aims to offer a hybrid stand-alone system for electric vehicle (EV) charging stations (CS), an emerging power scheme due to the availability of renewable and…
Abstract
Purpose
This study aims to offer a hybrid stand-alone system for electric vehicle (EV) charging stations (CS), an emerging power scheme due to the availability of renewable and environment-friendly energy sources. This paper presents the analysis of a photovoltaic (PV) with an adaptive neuro-fuzzy inference system (ANFIS) algorithm, solid oxide fuel cell (SOFC) and a battery storage scheme incorporated for EV CS in a stand-alone mode. In previous studies, either the hydrogen fuel of SOFC or the irradiance is controlled using artificial neural network. These parameters are not controlled simultaneously using an ANFIS-based approach. The ANFIS-based stand-alone hybrid system controlling both the fuel flow of SOFC and the irradiance of PV is discussed in this paper.
Design/methodology/approach
The ANFIS algorithm provides an efficient estimation of maximum power (MP) to the nonlinear voltage–current characteristics of a PV, integrated with a direct current–direct current (DC–DC) converter to boost output voltage up to 400 V. The issue of fuel starvation in SOFC due to load transients is also mitigated using an ANFIS-based fuel flow regulator, which robustly provides fuel, i.e. hydrogen per necessity. Furthermore, to ensure uninterrupted power to the CS, PV is integrated with a SOFC array, and a battery storage bank is used as a backup in the current scenario. A power management system efficiently shares power among the aforesaid sources.
Findings
A comprehensive simulation test bed for a stand-alone power system (PV cells and SOFC) is developed in MATLAB/Simulink. The adaptability and robustness of the proposed control paradigm are investigated through simulation results in a stand-alone hybrid power system test bed.
Originality/value
The simulation results confirm the effectiveness of the ANFIS algorithm in a stand-alone hybrid power system scheme.
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T.C. Venkateswarulu, Asra Tasneem Shaik, Druthi Sri Meduri, Vajiha Vajiha, Kalyani Dhusia and Abraham Peele
Mucorales has been described to be widely distributed during the most recent COVID-19 pandemic, with a greater frequency of disease in India, particularly among those with immune…
Abstract
Purpose
Mucorales has been described to be widely distributed during the most recent COVID-19 pandemic, with a greater frequency of disease in India, particularly among those with immune deficiencies. This study aims to use computational tools to develop a vaccine.
Design/methodology/approach
The authors investigated at Mucorales proteins that had previously been associated to virulence factors. Recent research suggests that a vaccine based on high-level cytotoxic T lymphocyte (CTL), helper T lymphocyte (HTL) and B-cell lymphocyte (BCL) epitopes from diverse proteins might be developed. Furthermore, the vaccine assembly contains the targeted epitopes as well as PADRE peptides to induce an immune response. Computational approaches were used to analyze the immunological parameters used to build the suggested vaccine and validate its TLR-3 binding.
Findings
These studies show that the vaccination is capable of triggering a particular immune response. The authors offer a technique for developing and evaluating candidate vaccines using computational tools. To the best of their knowledge, this is the first immunoinformatic research of a prospective mucormycosis vaccine.
Originality/value
During this audit, a successful attempt was made to create a subunit MEV against black fungus. In the current study, MEV has been proposed as a suitable neutralizer candidate since it is immunogenic, secure, stable and interacts with human receptors. A stream study, on the other hand, is produced via a mixed vaccinosis approach. Following that, vaccinologists may perform more exploratory testing to evaluate whether the vaccine is effective.
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Sajeda Al-Hadidi, Ghaleb Sweis, Waleed Abu-Khader, Ghaida Abu-Rumman and Rateb Sweis
Despite the enormous need to succeed in the urban model, scientists and policymakers should work consistently to create blueprints to regulate urbanization. The absence of…
Abstract
Purpose
Despite the enormous need to succeed in the urban model, scientists and policymakers should work consistently to create blueprints to regulate urbanization. The absence of coordination between the crucial requirements and the regional strategies of the local authorities leads to a lack of conformance in urban development. The purpose of this paper is to address this issue.
Design/methodology/approach
This study intends to manage future urban growth patterns using integrated methods and then employ the results in the genetic algorithm (GA) model to considerably improve growth behavior. Multi-temporal land-use datasets have been derived from remotely sensed images for the years 1990, 2000, 2010 and 2020. Urban growth patterns and processes were then analyzed with land-use-and-land-cover dynamics. Results were examined for simulation and utilization of the GA.
Findings
Model parameters were derived and evaluated, and a preliminary assessment of the effective coefficient in the formation of urbanization is analyzed, showing the city's urbanization pattern has followed along with the transportation infrastructure and outward growth, and the scattering rates are high, with an increase of 5.64% in building area associated with a decrease in agricultural lands and rangelands.
Originality/value
The research achieved a considerable improvement over the growth behavior. The conducted research design was the first of its type in that field to be executed to any specific growth pattern parameters in terms of regulating and policymaking. The method has integrated various artificial intelligence models to monitor, measure and optimize the projected growth by applying this design. Other research on the area was limited to projecting the future of Amman as it is an urbanized distressed city.
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Prapti Behera, Kannan N., Priyodip Paul, Sanjukta Aravind and Balaji S.
The textile sector struggles with cotton stickiness from honeydew contamination. It hurts agriculture and marketability. This study aims to examine how bacterial enzymes could…
Abstract
Purpose
The textile sector struggles with cotton stickiness from honeydew contamination. It hurts agriculture and marketability. This study aims to examine how bacterial enzymes could reduce honeydew-contaminated cotton adherence in textile businesses sustainably.
Design/methodology/approach
Enzyme was extracted from bacteria isolated from the fermented bamboo shoots “Lung siej”. The enzyme was tested for α-glucosidase using p-nitrophenyl-α-D-glucopyranoside as a substrate. Design of experiments determined enzyme activity temperature and reaction time. Laboratory-prepared artificial honeydew was added to ginning mill cotton to show honeydew contamination. After enzyme treatment, sticky cotton was tested for microscopic examination, ultraviolet (UV), Benedict’s, Elsner colorimetric, high volume instrument (HVI) and viscosity tests.
Findings
The bacterial isolate is characterized as Lysinibacillus sp. as confirmed by 16S rRNA gene sequencing. The enzyme extracted was identified as α-glucosidase. The ideal temperature and reaction time for enzymatic activity were 32 °C and 35 min, respectively, using central composite design. The microscopic examination, UV test, Benedict’s test, Elsner colorimetric test, HVI test and viscosity test showed that bacterial enzyme treatment reduced cotton fiber adherence.
Originality/value
Although few patents have examined the effect of yeast enzymes, to the best of the authors’ knowledge, a bacterial enzyme is investigated for the first time to reduce the adhesion of honeydew-contaminated cotton.
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Chad S. Seifried, Milorad M. Novicevic and Stephen Poor
This study aims to use a theoretical-based case study of two distinct ownership groups of the Jack Daniel’s brand to explore how rhetorical history (i.e. malleability of the past…
Abstract
Purpose
This study aims to use a theoretical-based case study of two distinct ownership groups of the Jack Daniel’s brand to explore how rhetorical history (i.e. malleability of the past for strategic goals) may evoke and capitalize on different forms of nostalgia. Within, the authors configure four forms of nostalgia (i.e. personal, historical, collective and cultural) from the individual or collective interaction and level of direct experience one has with the past as lived or happened.
Design/methodology/approach
This study uses an historical research approach which involved the identification of primary and secondary sources, facility tour, source criticism and triangulation to create themes of rhetorical history infused with nostalgic narratives using compelling evidence through rich description of this fusion.
Findings
The findings reveal how nostalgia-driven narratives reflecting different collective longing for the re-creation of an American Paradise Lost used by Jack Daniel (i.e. the man) and later but differently by Brown-Forman. This study uncovers how the company’s inherited past was used rhetorically throughout its history, beginning with the nostalgic story of Jack Daniel and the distillery’s nostalgically choreographed location in Lynchburg, Tennessee. This study delves into this setting to highlight the importance of symbols, details, emotional appeals and communications for collective memory and identity development and to showcase the ways in which they are influenced by different types and forms of nostalgia.
Originality/value
This study adds to a limited number of studies focused on understanding the impact of founders on an organization’s brand and how that is malleable. This study responds to scholarly calls to study the influence of sequenced historical rhetoric on an organization and highlight the relevance of social emotions such as nostalgia for rhetorical history. Finally, the theoretical contribution involves the advancing and construction of a theory typology of nostalgia previously proposed by Havlena and Holak in 1996.
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