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Mailed questionnaires were used to study the use of two printed current awareness devices in specialized areas of the neurosciences, one manually prepared and the other a product of MEDLARS. The study determined who uses each publication, how much, for what purpose, and with what degree of success. A major purpose was to discover how valuable the publications are to users and what impact they have had on their own research or professional practice as well as on their information seeking behaviour. Comparisons are made between the results for the two publications. Some conclusions are drawn on information seeking behaviour in the neuroscience community and on requirements for effective current awareness services in this field.

People with intellectual disability are subject to increased health morbidity when compared to the general population. This paper assesses the monitoring of metabolic syndrome in people with an intellectual disability who have been prescribed antipsychotic medication.

A pre‐audit analysis was followed by an audit of 32 patients. The height, weight and body mass index was recorded in 34 per cent prior to initiation, which decreased to 22 per cent at the three monthly follow up. Blood pressure was recorded in 6 per cent of the patients at baseline, but there was no record during treatment. The biochemical parameters including plasma glucose and plasma cholesterol were measured in 40 per cent of the patients on initiation which decreased to 33 per cent at three monthly follow up in the first year. In total, 21 per cent of patients received four monthly monitoring of the biochemical parameters, i.e. their height and weight, 25 per cent of the patients had an annual monitoring of all parameters.

The results indicate inconsistent monitoring of metabolic syndrome in people with intellectual disability being treated with antipsychotic medication. While a proportion of patients may have been monitored in primary care, these data indicate the need for remedial action to improve the standard of metabolic syndrome detection in those people with intellectual disability receiving antipsychotic medication.

This study highlights the inadequate monitoring of biochemical and physical parameters of metabolic syndrome in people with an intellectual disability who are prescribed antipsychotic medication. National criteria for monitoring the prescription of antipsychotic medication in people with intellectual disability who are prescribed antipsychotic medication is proposed.

Herbal medicine has been used for the management of complications of diabetes. The purpose of this paper is to examine the anti-diabetic effects of Achillea millefolium extract on diabetic rats.

To this aim, 32 male Wistar rats were randomly assigned into four groups in which each group comprised eight rats. The four experimental groups were as follows: control group, diabetic control (DC) group (STZ; 50 mg/kg), diabetic rats, receiving 250 mg/kg hydro-alcoholic extract of the A. millefolium (DAM) and diabetic rats, receiving 5 mg/kg glibenclamide (DG). After 21 days of the treatment course, tissues of the kidney and blood samples were collected for histopathological, biochemical and molecular analysis.

The concentration of malondialdehyde (MDA) and glucose serum were markedly reduced in the DC group while significantly increased in DG and DAM groups (1.11 ± 0.57 to 19.4 ± 3.5 and 17.8 ± 1.2 p = 0.002 and 325 ± 0.18 to 223 ± 0.11 and 211 ± 0.32 p = 0.02, respectively). Also, the activities of glutathione peroxidase (GPx) and superoxide dismutase (SOD) were markedly reduced in the DC group while significantly increased in DAM and DG groups (9.1 ± 2.21 to 18.7 ± 3.81 and 14.9 ± 3.1 p = 0.03 and p = 0.02, respectively). The concentrations of creatinine, blood urea nitrogen (BUN) and urea were substantially decreased in DAM and DG groups as compared with the DC group (0.49 ± 0.02 to 0.27 ± 0.01 and 0.25 ± 0.01 p = 0.01, 15.6 ± 2.1 to 7.2 ± 0.68 and 8.6 ± 1.2 p = 0.02 and 114 ± 9.4 to 59.8 ± 5.2 and 64 ± 5.2 p = 0.03, respectively). Also, Bcl-2-associated X protein (BAX) expression was significantly decreased in DAM and DG groups as compared with the DC group (1.3 ± 0.32 to 0.91 ± 0.03 and 0.93 ± 0.02 p = <0.01) and Bcl-2 expression were significantly increased in DAM and DG groups as compared with the DC group (0.42 ± 0.05 to 0.88 ± 0.07 and 0.85 ± 0.06 p = 0.01).

Diabetes led to degenerative damages in the kidney of rats and increased the mRNA level of Bax, while treatment with A. millefolium could protect the kidney tissue against diabetes complications and increased the mRNA expression of Bcl-2. This study indicated that A. millefolium extracts not only improves renal function as a result of anti-oxidant activity but also modulates some biochemical factors in diabetic rats.

This study was aimed to develop and evaluate nutritional efficacy and bio-efficacy of food products from plantain, soycake, rice-bran and oat-bran flour.

The flour samples were blended as follows: plantain 70% and soycake 30% (PS); plantain 65%, soycake 30% and rice bran 5% (PSR); plantain 65%, soycake 30% and oat bran 5% (PSO); and plantain 60%, soycake 30%, rice bran 5% and oat bran 5% (PSRO). Antioxidant and nutritional properties of the blended foods and controls (100% plantain and Cerolina) were determined.

Protein (16.2–19.4 g/100g) and biological values (98.5–99.3%) of the food samples were significantly (p = 0.03) higher than 100% plantain (5 g/100g, 31.6%) and Cerolina (17.9 g/100g, 98.3%). Pack cell volume (36.2–42%), serum protein (7.3–9.3 mg/dL), urea/creatinine (1.1–2.8) and aspartate-aminotransferase/alanine-aminotransferase ratio (0.9–1) of the foods were significantly (p = 0.03, 0.01, 0.02 and <0.01, respectively) higher than 100% plantain (28%, 1.6 mg/dL, 4.6 and 0.8) and Cerolina (46%, 4.9 mg/dL, 3 and 0.73). In vivo antioxidant activity of the food samples decreased from PSRO to PSO, PSR and PS, respectively and were higher than control samples. Nutritional performance of formulated foods in rats was similar to that of Cerolina, but higher than in 100% plantain. Cerolina and 100% plantain were rated higher in overall acceptability than formulated foods; however, PSO was most preferred followed by PSRO for the formulated foods.

The study established that PSRO was rated best in terms of nutrition, growth performance and antioxidant activities. Hence, this food may be suitable as functional food to prevent malnutrition and oxidative stress.

This article briefly outlines the main objectives of the Ministry of Agriculture, Fisheries and Food (MAFF) programme of research in support of dietary surveys. It summarises the current portfolio of projects, then discusses in more depth the six projects being undertaken on further analysis of data from government dietary surveys, drawing on papers presented by the researchers at the annual meeting of this programme in London on 2 June 1998.

The purpose of this paper is to assess the nutritional status and quality of life in patients according to the clinical severity of liver cirrhosis.

A total of 151 cirrhotics were selected for study. Nutritional assessment was done by anthropometry, subjective global assessment, malnutrition universal screening tool, biochemical estimations and 72‐hour dietary recall. Quality of life was assessed by chronic liver disease questionnaire.

Child's status was A/B/C in 29/68/59, respectively. Muscle and fat depletion was significantly higher in grade C patients as compared to grade A and B patients. Incidence of malnutrition was lowest in grade A patients (72.4 percent) and highest in grade C patients (90.74 percent) (p = 0.00). Calorie and protein intake was significantly lower in grade C patients compared to grade A and B patients (p = 0.00). Child Pugh score was found to be an independent risk factor for various nutritional and clinical parameters.

The data presented reflect the assessment of a very small cohort of these patients and should be done on a larger scale.

Looking into the high prevalence of malnutrition and the negative impact of disease severity, nutritional assessment of these patients should be done on a regular basis and nutritional therapy planned accordingly.

Data on malnutrition from India are scarce. This study is a small attempt to throw light on the nutritional status and its variation according to clinical severity of liver cirrhosis.

Understanding how health status and physiological factors affect performance is a daunting task. This chapter will discuss physiological, behavioral, and psychological factors that influence or determine the capacity to fight, and will consider metrics that can be used to measure their status. The premise of this discussion is that there is a set of physiological and psychological factors that intimately affect performance and that the relative contribution of these variables is individually unique. These factors can be identified and assessed, and are amenable to modification. A fuller understanding of these variables can lead the effort to maintain and improve performance in the adverse and challenging environments of military operations.

Obesity can cause impairment in adipose tissue-derived hormones levels, which, in turn, might lead to metabolic syndrome occurrence. This study aims to assess the relationship between the levels of adiponectin, resistin, retinol-binding protein 4 (RBP4) and insulin with metabolic syndrome (MetS) indices. Also, optimal cutoff points of the adipokines and insulin for MetS prediction were determined.

In this study, 180 women (90 women with MetS and 90 women without MetS) were studied. The National Cholesterol Education Program Adult Treatment Panel III criteria were used for MetS diagnosis. Anthropometric and biochemical indices were measured. Data were analyzed using SPSS software version 21.

Serum adiponectin correlated negatively with age, BMI, waist circumference (WC), triglyceride (TG), total cholesterol, SBP, DBP, FBS and positively correlated with high-density lipoprotein-cholesterol. Both resistin and RBP4 levels correlated positively with BMI, WC, TG, SBP, DBP and FBS. Also, serum insulin correlated positively with BMI, WC, SBP and DBP. All the studied adipokines and insulin showed significant areas under the receiver operating characteristics curve. The largest area under the curve was observed for adiponectin (0.93, 95 per cent CI = 0.89-0.97, p < 0.001) with the optimal cut-off point of 11.94 µg/L. Also, the upper level of adiponectin was associated with 70 per cent lower prevalence odds of metabolic syndrome after adjusting for confounders.

The authors determined the optimal cutoff points of the adipokines and insulin for MetS prediction and calculated the diagnostic odds ratio for various cutoff values. Adiponectin could be used as a biomarker in MetS regarding its largest AUC.

Vegetarian diets exclude meat, fish and poultry and/or egg and dairy products, these diets are based on grains, fruits, vegetables, legumes and seeds. The purpose of this study is to compare the nutritional status between lacto-ovo vegetarian and non-vegetarian Jordanian adults.

A case-control study was conducted during the period between (April–November 2019). In total, 200 Jordanians in early adulthood aged between 18 and 35 years participated in the present study; 100 subjects were non-vegetarians and 100 subjects were lacto-ovo vegetarians. The ratio was (1:1). Matching between the two groups was done in terms of age, sex and body mass index. A package that consisted of three structured questionnaires: Personal Information Sheet, Food Frequency Questionnaire and Seven-Day Physical Activity Recall were administered to all participants in this study.

The concentration of serum vitamin B12 was significantly higher (P = 0.011) in non-vegetarians than lacto-ovo vegetarians. The means of intake of calories (P = 0.003), calories from fat (P = 0.001), calories from saturated fat (P = 0.001), protein (P = 0.001), fat (P = 0.001), saturated fat (P = 0.001), monounsaturated fat (P = 0.022), polyunsaturated fat (P = 0.001), cholesterol (P = 0.001) and omega-6 (P = 0.039) were significantly higher in non-vegetarians. The intakes Mean of carbohydrates (P = 0.001), fiber (P = 0.001) and soluble fiber (P = 0.001) were significantly higher in lacto-ovo vegetarians compared to non-vegetarians. The mean of beta-carotene intake was significantly higher (P = 0.001) in lacto-ovo vegetarians compared to non-vegetarians, although the intakes of vitamin A(RAE) and retinol were significantly higher (P = 0.029, P = 0.001, respectively) in non-vegetarians as compared to lacto-ovo vegetarians. The means of vitamins B2 (P = 0.018), B3 (P = 0.001), B3NE (P = 0.001), B6 (mg) (P = 0.001), B12 (P = 0.001), E-a-Tocopherol (P = 0.001) and D (P = 0.001) intake were significantly higher in non-vegetarians compared to lacto-ovo vegetarians. The mean intakes of vitamins C (P = 0.033), folate (P = 0.005) and K (P = 0.002) were significantly in lacto-ovo vegetarians compared to non-vegetarians. Means intake of some minerals was significantly higher in non-vegetarians than lacto-ovo vegetarians.

The current study showed that lacto-ovo vegetarians had lower serum vitamin B12 levels. The consumption of fruits, vegetables and legumes was higher in lacto-ovo vegetarians than non-vegetarians. While lacto-ovo vegetarian diet provided less fat, saturated fat, polyunsaturated fat, monounsaturated fat and cholesterol than non-vegetarians, it could be considered a rich source for fiber, folate, beta-carotene, vitamin C and vitamin K.

The purpose of this paper is a single-center six-month follow-up study to determine nutritional status of children with maple syrup urine disease (MSUD). Prolonged restriction on essential amino acid could cause malnutrition. By far, there is no study reported in the context of nutritional status among children with maple syrup urine disease (MSUD), who required life-long protein restriction.

A total of 22 children with MSUD, aged from 1 to 12 years (6.54 ± 3.27) undergoing regular treatment in Institute of Pediatrics, Hospital Kuala Lumpur, were recruited. Body height, weight and head circumference were measured for anthropometry, whereas total protein, albumin and plasma branched-chain amino acid were measured for biochemical aspects. Clinical features diagnosed by pediatrician were recorded from children’s medical record. The 24-hour dietary recall was conducted to measure their nutrients intake. All assessments were repeated at six-month interval except clinical profile.

There were no significant differences in all nutritional parameters from baseline to end of the visit. There was a prominence (particular noticeable of) of growth stunting (68; 64 per cent), undernutrition (35; 32 per cent) and microcephalic (57; 57 per cent) among children with MSUD. Nevertheless, children showed no significant improvement of anthropometric variables from baseline and after 6-month follow-up visit. Nearly all biochemical indicators were significantly (p < 0.05) higher than the reference value except valine. Intellectual disability was the most frequently (71 per cent) presenting symptoms among them. The finding also did not show any macro- or micronutrients fail to achieve above recommended nutrient intake in both visits. In conclusion, it is clear that no significant nutritional deficiency was induced by the use of MSUD dietary therapy; however, the findings indicated that MSUD children are at risk of malnutrition and regular nutritional assessment and monitoring should always be emphasized for optimal linear growth without affecting their amino acid profiles.

Multiple 24-hour recalls instead of single 24-hour recall should be used in this study for a better estimate of intake.

Although there are retrospective studies targeted in presenting the clinical and biochemical profile of MSUD children which has been extensively examined, limited research has focused on prospective aspect of nutritional status of these children who are undergoing active and regular diet and medical nutrition therapy because of the absence of comprehensive reliable nutritional assessment data.