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About 70% of all aircraft accidents are caused by human–machine interaction, thus identifying and quantifying performance shaping factors is a significant challenge in the study of human reliability. An information flow field model of human–machine interaction is put forward to help better pinpoint the factors influencing performance and to make up for the lack of a model of information flow and feedback processes in the aircraft cockpit. To enhance the efficacy of the human–machine interaction, this paper aims to examine the important coupling factors in the system using the findings of the simulation.

The performance-shaping factors were retrieved from the model, which was created to thoroughly describe the information flow. The coupling degree between the performance shaping factors was calculated, and simulation and sensitivity analysis are based on system dynamics.

The results show that the efficacy of human–computer interaction is significantly influenced by individual important factors and coupling factors. To decrease the frequency of accidents after seven hours, attention should be paid to these factors.

The novelty of this work lies in proposing a theoretical model of cockpit information flow and using system dynamics to analyse the effect of the factors in the human–machine loop on human–machine efficacy.

This survey explores the application of real options theory to the field of health economics. The integration of options theory offers a valuable framework to address these challenges, providing insights into healthcare investments, policy analysis and patient care pathways.

This research employs the real options theory, a financial concept, to delve into health economics challenges. Through a systematic approach, three distinct models rooted in this theory are crafted and analyzed. Firstly, the study examines the value of investing in emerging health technology, factoring in future advantages, associated costs and unpredictability. The second model is patient-centric, evaluating the choice between immediate treatment switch and waiting for more clarity, while also weighing the associated risks. Lastly, the research assesses pandemic-related government policies, emphasizing the importance of delaying decisions in the face of uncertainties, thereby promoting data-driven policymaking.

Three different real options models are presented in this study to illustrate their applicability and value in aiding decision-makers. (1) The first evaluates investments in new technology, analyzing future benefits, discount rates and benefit volatility to determine investment value. (2) In the second model, a patient has the option of switching treatments now or waiting for more information before optimally switching treatments. However, waiting has its risks, such as disease progression. By modeling the potential benefits and risks of both options, and factoring in the time value, this model aids doctors and patients in making informed decisions based on a quantified assessment of potential outcomes. (3) The third model concerns pandemic policy: governments can end or prolong lockdowns. While awaiting more data on the virus might lead to economic and societal strain, the model emphasizes the economic value of deferring decisions under uncertainty.

This research provides a quantified perspective on various decisions in healthcare, from investments in new technology to treatment choices for patients to government decisions regarding pandemics. By applying real options theory, stakeholders can make more evidence-driven decisions.

Decisions about patient care pathways and pandemic policies have direct societal implications. For instance, choices regarding the prolongation or ending of lockdowns can lead to economic and societal strain.

The originality of this study lies in its application of real options theory, a concept from finance, to the realm of health economics, offering novel insights and analytical tools for decision-makers in the healthcare sector.