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Open Access
Article
Publication date: 25 March 2021

Santhosh J. Thattil and T.A. Ajith

Severe bacterial infection is a major cause of neonatal morbidity and mortality worldwide. Geographical-based demographic laboratory and clinical data are required to get a…

Abstract

Purpose

Severe bacterial infection is a major cause of neonatal morbidity and mortality worldwide. Geographical-based demographic laboratory and clinical data are required to get a conclusion about the bacterial infection and their antibiotic susceptibility for the empiric antibiotic treatment in infants who presented with suspected infection. This study was aimed to find the most prevalent bacterial infection and antibiotic sensitivity among infants in the post-neonatal period presented at a tertiary care centre in South India.

Design/methodology/approach

A cross-sectional study was designed among infants (29 days to 1 year old) presented with suspected infection in the paediatric department. Infants with positive culture report were analysed for the bacteriological and antibiotic profile from the medical records. Antibiotic sensitivity was determined for the isolated bacteria according to standard procedure and data statically analysed.

Findings

Total of 218 samples (138 male and 80 female) were analysed. Most of the samples (171/218, 78.4%) were throat swab (p = 0.0247). Only one sample was cerebrospinal fluid from case of meningitis. Sample from upper RTI was major (162/218, 74.3%) with male dominance followed by stool samples from cases of diarrhoea (22/218, 10.0%). Staphylococcus aureus was the major organism identified in 46/171 (26.9 %) throat swabs. The most sensitive antibiotic against bacteria isolated from throat swab and CSF was gentamicin and cloxacillin. Netilmicin and piperacillin plus tazobactam were the sensitive antibiotics against bacteria isolated from stool, ear secretion and urine samples.

Originality/value

Upper RTI was the prevalent bacterial infection followed by diarrhoea in infants in the post-neonatal period. Klebsiella pneumoniae was the common organism identified in the overall report followed by E. coli and S. aureus. Community-based awareness should be provided to follow good hygiene regularly in child care. Furthermore, avoid delay in seeking treatment and provide the medicine prescribed at the right time and in the right dose to limit the morbidity and bacterial resistance.

Details

Journal of Health Research, vol. 36 no. 2
Type: Research Article
ISSN: 0857-4421

Keywords

Content available
Article
Publication date: 1 December 2001

48

Abstract

Details

Nutrition & Food Science, vol. 31 no. 6
Type: Research Article
ISSN: 0034-6659

Content available
Article
Publication date: 19 October 2010

76

Abstract

Details

Clinical Governance: An International Journal, vol. 15 no. 4
Type: Research Article
ISSN: 1477-7274

Content available
Article
Publication date: 26 April 2011

149

Abstract

Details

Clinical Governance: An International Journal, vol. 16 no. 2
Type: Research Article
ISSN: 1477-7274

Open Access
Article
Publication date: 31 October 2022

Ouafae El Yahyaoui, Bahia Bouabid, Nabil Ait Ouaaziz, Mohamed El Bakkali, Hanae El Harche, Lalla Aicha Lrhorfi, Kamal Nakari and Rachid Bengueddour

Within the framework of the valorization of natural resources, a characterization of the biochemical composition of the edible parts of Adansonia Digitata is applied. The…

1366

Abstract

Purpose

Within the framework of the valorization of natural resources, a characterization of the biochemical composition of the edible parts of Adansonia Digitata is applied. The antibacterial effect against bacteria is also realized and compared to some synthetic antibiotics.

Design/methodology/approach

The biochemical characterization is carried out according to the norms of the French Association of Normalization, methods of Association of Official Analytical Chemists (AOAC International) and gas chromatography (GC). The antibacterial activity is tested by disk diffusion on a solid medium. Parametric tests are used to compare the differences between groups and heat maps to show the expression of the mean inhibitions according to the studied parameters. Multivariate logistic modeling is applied to study the effect of extracts and antibiotics on bacteria.

Findings

Biochemical characterization showed a variable importance of proteins, fibers and total sugars, with the presence of highly desired fatty acids such as palmitic, oleic, stearic, linoleic and a-linolenic acids. This gives the tested parts important energy values, especially in the seeds very rich in fatty acids. Methanol proved to be a better extraction solvent than dichloromethane. Antibacterial activity showed that pulp and leaves extracted with methanol had quite similar inhibitory activities against Enterococcus faecalis ATCC29212 and that this effect was better than some antibiotics. Multivariate analysis showed that the leaves had a similar effect to antibiotics, and a significant effect against Staphylococcus aureus ATCC29213.

Originality/value

This important activity and the attractive nutritional value of this plant could justify its extensive use in the traditional pharmacopoeia.

Details

Arab Gulf Journal of Scientific Research, vol. 41 no. 1
Type: Research Article
ISSN: 1985-9899

Keywords

Content available
Article
Publication date: 1 December 1999

Stephen Fallows

44

Abstract

Details

British Food Journal, vol. 101 no. 11
Type: Research Article
ISSN: 0007-070X

Content available
Article
Publication date: 1 April 2000

Dr Stephen Fallows

73

Abstract

Details

Nutrition & Food Science, vol. 30 no. 2
Type: Research Article
ISSN: 0034-6659

Content available
Article
Publication date: 1 February 1998

G. Tansey

282

Abstract

Details

European Business Review, vol. 98 no. 1
Type: Research Article
ISSN: 0955-534X

Content available
Book part
Publication date: 8 April 2024

Amaresh Panda and Sanjay Mohapatra

Abstract

Details

The Online Healthcare Community
Type: Book
ISBN: 978-1-83549-141-6

Content available
Article
Publication date: 1 August 2000

170

Abstract

Details

British Food Journal, vol. 102 no. 7
Type: Research Article
ISSN: 0007-070X

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