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This study aims to estimate the overall SARS-CoV-2 seroprevalence and evaluate the accuracy of an antibody rapid test compared to a reference serological assay during a COVID-19 outbreak in a prison complex housing over 13,000 prisoners in Brasília.

The authors obtained a randomized, stratified representative sample of each prison unit and conducted a repeated serosurvey among prisoners between June and July 2020, using a lateral-flow immunochromatographic assay (LFIA). Samples were also retested using a chemiluminescence enzyme immunoassay (CLIA) to compare SARS-CoV-2 seroprevalence and 21-days incidence, as well as to estimate the overall infection fatality rate (IFR) and determine the diagnostic accuracy of the LFIA test.

This study identified 485 eligible individuals and enrolled 460 participants. Baseline and 21-days follow-up seroprevalence were estimated at 52.0% (95% CI 44.9–59.0) and 56.7% (95% CI 48.2–65.3) with LFIA; and 80.7% (95% CI 74.1–87.3) and 81.1% (95% CI 74.4–87.8) with CLIA, with an overall IFR of 0.02%. There were 78.2% (95% CI 66.7–89.7) symptomatic individuals among the positive cases. Sensitivity and specificity of LFIA were estimated at 43.4% and 83.3% for IgM; 46.5% and 91.5% for IgG; and 59.1% and 77.3% for combined tests.

The authors found high seroprevalence of anti-SARS-CoV-2 antibodies within the prison complex. The occurrence of asymptomatic infection highlights the importance of periodic mass testing in addition to case-finding of symptomatic individuals; however, the field performance of LFIA tests should be validated. This study recommends that vaccination strategies consider the inclusion of prisoners and prison staff in priority groups.

The COVID-19 pandemic emphasises the need for antiviral materials that can reduce airborne and surface-based virus transmission. This study aims to propose the use of additive manufacturing (AM) and surrogate modelling for the rapid development and deployment of novel copper-tungsten-silver (Cu-W-Ag) microporous architecture that shows strong antiviral behaviour against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

The research combines selective laser melting (SLM), in-situ alloying and surrogate modelling to conceive the antiviral Cu-W-Ag architecture. The approach is shown to be suitable for redistributed manufacturing by representing the pore morphology through a surrogate model that parametrically manipulates the SLM process parameters: hatch distance (h_d), scan speed (S_s) and laser power (L_p). The method drastically simplifies the three-dimensional (3D) printing of microporous materials by requiring only global geometrical dimensions solving current bottlenecks associated with high computed aided design data transfer required for the AM of porous materials.

The surrogate model developed in this study achieved an optimum parametric combination that resulted in microporous Cu-W-Ag with average pore sizes of 80 µm. Subsequent antiviral evaluation of the optimum architecture showed 100% viral inactivation within 5 h against a biosafe enveloped ribonucleic acid viral model of SARS-CoV-2.

The Cu-W-Ag architecture is suitable for redistributed manufacturing and can help reduce surface contamination of SARS-CoV-2. Nevertheless, further optimisation may improve the virus inactivation time.

The study was extended to demonstrate an open-source 3D printed Cu-W-Ag antiviral mask filter prototype.

The evolving nature of the COVID-19 pandemic brings new and unpredictable challenges where redistributed manufacturing of 3D printed antiviral materials can achieve rapid solutions.

The papers present for the first time a methodology to digitally conceive and print-on-demand a novel Cu-W-Ag alloy that shows high antiviral behaviour against SARS-CoV-2.

Prisons can be epicentres of infectious diseases. However, empirical evidence on the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in prison is still scarce. This study aims to estimate the seroprevalence rates of anti-SARS-CoV-2 in the largest and most crowded Swiss prison and compare them with the seroprevalence rate in the general population.

A cross-sectional study was conducted in June 2020, one month after the first wave of SARS-CoV-2 in Switzerland. Groups included: people living in detention (PLDs) detained before the beginning of the pandemic (n = 116), PLDs incarcerated after the beginning of the pandemic (n = 61), prison staff and prison healthcare workers (n = 227) and a sample from the general population in the same time period (n = 3,404). The authors assessed anti-SARS-CoV-2 IgG antibodies.

PLDs who were incarcerated before the beginning of the pandemic had a significantly lower seroprevalence rate [0.9%, confidence interval (CI)95%: 0.1%–5.9%] compared to the general population (6.3%, CI 95%: 5.6–7.3%) (p = 0.041). The differences between PLDs who were incarcerated before and other groups were marginally significant (PLDs incarcerated after the beginning of the pandemic: 6.6%, CI 95%: 2.5%–16.6%, p = 0.063; prison staff CI 95%: 4.8%, 2.7%–8.6%, p = 0.093). The seroprevalence of prison staff was only slightly and non-significantly lower than that of the general population.

During the first wave, despite overcrowding and interaction with the community, the prison was not a hotspot of SARS-CoV-2 infection. Preventive measures probably helped avoiding clusters of infection. The authors suggest that preventive measures that impact social welfare could be relaxed when overall circulation in the community is low to prevent the negative impact of isolation.

Under the strong leadership of Chinese Government to the anti‐SARS struggle, the situation has been successfully controlled. Since May 1 of 2003, the Ministry of Health of China published daily the number of newly increased SARS patient of Beijing, the authors analyzed these data using X_cs−X_scs cause‐selecting control charts of Statistical Diagnosis (SPD) Theory. Data about number of newly increased SARS patient consists of two kinds of variation: random variation and tendency variation of SARS epidemic. It is concluded that SARS epidemic of Beijing was already controlled since May 9 of 2003.

The nutritional and anthropometric status can be essential in determining their immune response to vaccines. The purpose of this paper was to investigate the association between diet quality and anthropometric indices with the side effects of the Pfizer-BioNTech COVID-19 vaccine and the SARS-CoV-2 immunoglobulin G titer among Kurdish adults.

This cross-sectional survey-based study was conducted between December 2021 and February 2022. This paper included data on 115 adults, 20–89 years old, from the Kurdistan region. Dietary information was collected using a short food frequency questionnaire, and diet quality was assessed using a plant-based healthy diet score. A blood test was performed to measure the SARS-CoV-2 immunoglobin G (IgG) titer after the vaccination's first and second doses.

Overweight and obese subjects reported more local pain, myalgia, headache, local bruising and local reactions after receiving the first dose of the vaccine (p = 0.04). People on a less healthy diet reported more local pain, myalgia and headache (p = 0.04) and more local bruising and reactions (p = 0.01) after receiving the second dose of the vaccine. On the other hand, the authors observed that those with healthy dietary habits had more IgG titer after the first and second doses of vaccination than those with less healthy dietary habits (p = 0.001).

The results showed that participants with a healthy diet and normal weight status had fewer side effects of the Pfizer-BioNTech COVID-19 vaccine than obese people and those with a less healthy diet.

Social movements, justice campaigns and civil activism have gained recent scholarly attention among non-Western democracies since the end of the Cold War. Yet the meaning and practical implications of civil activism remain contested especially in contexts linked to militarised democracy and the criminalisation of civil activism. Importantly, the broader political terrain within which militarised democracy is situated is increasingly changing, bringing new challenges to its understanding. This chapter builds on liberal democratic theory and discusses militarised democracy in Nigeria to critique state-centric notion of criminology. It draws on two case examples, namely the proscription of the Indigenous People of Biafra (IPOB) in 2017 by the federal government against its organised protests for self-determination and the state repressive response to the nation-wide protest against police brutality of the Special Anti-Robbery Squad (SARS) known as the #End SARS protest in 2020. Both provide on-the-ground evidence of the criminalisation of civil activism. In the alternative, this chapter reflects on how transforming democracy can redress state repression and offer a better understanding of civil activism, which can strengthen developing democracies, including addressing questions of political marginalisation, distributive justice, police brutality, inequality, repressive state response and unequal state structure accounting for organised protests.

Most research ethic review procedures refer to the principles of safety and security only as sub-criteria of other ethical principles such as the protection of human subjects in research, thereby ignoring the public good aspect of safety and security. In addition, Research Ethics Review Committees (RECs) are usually dominated by philosophers, ethicists, medical doctors, and lawyers with limited practical backgrounds in safety and security risk management. This gap of knowledge restricts ethics reviews in carrying out project-specific safety and security risk management and defers this responsibility to lawmakers and national legal authorities. What might be sufficient in well-regulated and well-understood environments, such as the safety of individuals during clinical research, is insufficient in managing rapidly changing and emerging risks – such as with emerging biotechnologies – as well as addressing the public good dimension of safety and security.

This chapter considers governance approaches to safety and security in research. It concludes that legal mechanisms are insufficient to cope with the complexity of and the fast progress made in emerging technologies. The chapter also addresses the role and potential of research ethics as a safety and security governance approach. It concludes that research ethics can play an important role in the governance of such risks arising from emerging technologies, for example through fundamental rights and public good considerations. However, in reality the current capacity of ethics in the safety and security governance of emerging technologies is limited. It is argued that in newly emerging areas of research currently applied legal compliance–based approaches are insufficient. Instead, inclusion of fundamental risk management knowledge and closer interactions between scientists, safety, and security experts are needed for effective risk management. Safety and Security Culture provide frameworks for such interactions and would well complement the current legal compliance–based governance approaches in research ethics.

The COVID-19 pandemic and its related economic meltdown and social unrest severely challenged most countries, their societies, economies, organizations, and individual citizens. Focusing on both more and less successful country-specific initiatives to fight the pandemic and its multitude of related consequences, this chapter explores implications for leadership and effective action at the individual, organizational, and societal levels. As international management scholars and consultants, the authors document actions taken and their wide-ranging consequences in a diverse set of countries, including countries that have been more or less successful in fighting the pandemic, are geographically larger and smaller, are located in each region of the world, are economically advanced and economically developing, and that chose unique strategies versus strategies more similar to those of their neighbors. Cultural influences on leadership, strategy, and outcomes are described for 19 countries. Informed by a cross-cultural lens, the authors explore such urgent questions as: What is most important for leaders, scholars, and organizations to learn from critical, life-threatening, society-encompassing crises and grand challenges? How do leaders build and maintain trust? What types of communication are most effective at various stages of a crisis? How can we accelerate learning processes globally? How does cultural resilience emerge within rapidly changing environments of fear, shifting cultural norms, and profound challenges to core identity and meaning? This chapter invites readers and authors alike to learn from each other and to begin to discover novel and more successful approaches to tackling grand challenges. It is not definitive; we are all still learning.

The purpose of this study is to identify, analyse and model the post-processing barriers of 3D-printed medical models (3DPMM) printed by fused deposition modelling to overcome these barriers for improved operational efficiency in the Indian context.

The methodology used interpretive structural modelling (ISM), cross-impact matrix multiplication applied to classification (MICMAC) analysis and decision-making trial and evaluation laboratory (DEMATEL) to understand the hierarchical and contextual relations among the barriers of the post-processing.

A total of 11 post-processing barriers were identified in this study using ISM, literature review and experts’ input. The MICMAC analysis identified support material removal, surface finishing, cleaning, inspection and issues with quality consistency as significant driving barriers for post-processing. MICMAC also identified linkage barriers as well as dependent barriers. The ISM digraph model was developed using a final reachability matrix, which would help practitioners specifically tackle post-processing barriers. Further, the DEMATEL method allows practitioners to emphasize the causal effects of post-processing barriers and guides them in overcoming these barriers.

There may have been a few post-processing barriers that were overlooked by the Indian experts, which might have been important for other country’s perspective.

The presented ISM model and DEMATEL provide directions for operation managers in planning operational strategies for overcoming post-processing issues in the medical 3D-printing industry. Also, managers may formulate operational strategies based on the driving and dependence power of post-processing barriers as well as the causal effects relationships of the barriers.

This study contributes to identifying, analyzing and modelling the post-processing barriers of 3DPMM through a combined ISM and DEMATEL methodology, which has not yet been reviewed. This study also contributes to decision makers developing suitable strategies to overcome the post-processing barriers for improved operational efficiency.

The present digital world’s challenging issue is COVID-19. This paper is related to the process of the COVID-19 treatment based on age, gender, symptoms and previous health issues. This paper gives the deep discussion about the prevention, symptoms, tests and treatment process. In this research work, the discussion is about vaccine invention and the side effects of the consumed medication.

This paper gives a clear explanation of the types of vaccine, which are lopinavir, ritonavir, remdesivir, hydroxychloroquine, chloroquine and plasma therapy. Thereafter, the discussion is prolonged to Indian vaccine for COVID-19.

This paper examines some of the COVID-19 treatment processes and difficulties, and finally, this paper aims to summarize and give an overview of the present preclinical research and clinical trials of potential candidates for COVID-19 treatments and vaccines.

The required information has been taken from online databases such as PubMed, Science, Nature, PNAS and Cell. Papers included were published between December 2019 and July 2020. The current results indicate the most promising outcomes for dexamethasone as a treatment and vaccine. Further research is needed to identify safe and effective treatments and vaccines for COVID-19.