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Article

Xingya Wang and Guangchang Pang

This paper aims to provide a detailed review of weak interaction biosensors and several common biosensor methods for magnifying signals, as well as judiciously guide…

Abstract

Purpose

This paper aims to provide a detailed review of weak interaction biosensors and several common biosensor methods for magnifying signals, as well as judiciously guide readers through selecting an appropriate detecting system and signal amplification method according to their research and application purpose.

Design/methodology/approach

This paper classifies the weak interactions between biomolecules, summarizes the common signal amplification methods used in biosensor design and compares the performance of different kinds of biosensors. It highlights a potential electrochemical signal amplification method: the G protein signaling cascade amplification system.

Findings

Developed biosensors which, based on various principles, have their own strengths and weaknesses have met the basic detection requirements for weak interaction between biomolecules: the selectivity, sensitivity and detection limit of biosensors have been consistently improving with the use of new signal amplification methods. However, most of the weak interaction biosensors stop at the research stage; there are only a minority realization of final commercial application.

Originality/value

This paper evaluates the status of research and application of weak interaction biosensors systematically. The G protein signaling cascade amplification system proposal offers a new avenue for the research and development of electrochemical biosensors.

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Article

Matloub Hussain and Paul R. Drake

The purpose of this paper is to analyze the effect of batching on bullwhip effect in a model of multi‐echelon supply chain with information sharing.

Abstract

Purpose

The purpose of this paper is to analyze the effect of batching on bullwhip effect in a model of multi‐echelon supply chain with information sharing.

Design/methodology/approach

The model uses the system dynamics and control theoretic concepts of variables, flows, and feedback processes and is implemented using iThink® software.

Findings

It has been seen that the relationship between batch size and demand amplification is non‐monotonic. Large batch sizes, when combined in integer multiples, can produce order rates that are close to the actual demand and produce little demand amplification, i.e. it is the size of the remainder of the quotient that is the determinant. It is further noted that the value of information sharing is greatest for smaller batch sizes, for which there is a much greater improvement in the amplification ratio.

Research limitations/implications

Batching is associated with the inventory holding and backlog cost. Therefore, future work should investigate the cost implications of order batching in multi‐echelon supply chains.

Practical implications

This is a contribution to the continuing research into the bullwhip effect, giving supply chain operations managers and designers a practical way into controlling the bullwhip produced by batching across multi‐echelon supply chains. Economies of scale processes usually favor large batch sizes. Reducing batch size in order to reduce the demand amplification is not a good solution.

Originality/value

Previous similar studies have used control theoretic techniques and it has been pointed out that control theorists are unable to solve the lot sizing problem. Therefore, system dynamic simulation is then applied to investigate the impact of various batch sizes on bullwhip effect.

Details

International Journal of Physical Distribution & Logistics Management, vol. 41 no. 8
Type: Research Article
ISSN: 0960-0035

Keywords

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Book part

Nicola Osborne

Social media tools are in increasing use across higher education and Twitter hashtags, live blogs, Facebook events, and Flickr groups are becoming a regular feature of…

Abstract

Social media tools are in increasing use across higher education and Twitter hashtags, live blogs, Facebook events, and Flickr groups are becoming a regular feature of academic conferences and event. In this chapter the author reflects on the experience of planning, moderating, and analyzing social media amplification of the 2009 Beyond the Repository Fringe event. Based upon this experience several important issues regarding social media usage are considered and a series of practical guidelines for planning amplification of higher education events are proposed.

Details

Higher Education Administration with Social Media
Type: Book
ISBN: 978-0-85724-651-6

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Article

David H. Taylor

The Demand Amplification Effect has been well described in the literature over many years, yet it is clear that the effect is still prevalent in many supply chains. In…

Abstract

The Demand Amplification Effect has been well described in the literature over many years, yet it is clear that the effect is still prevalent in many supply chains. In this paper, a practical approach is described for identifying and measuring demand amplification. The approach was applied within the upstream automotive component supply chain in the U.K. The causes of demand amplification within this scenario are analyzed and compared to those identified in previous work. The work described is the first part of a wider project, the aim of which is to develop a comprehensive approach to enable management to counteract the problem of demand amplification.

Details

The International Journal of Logistics Management, vol. 10 no. 2
Type: Research Article
ISSN: 0957-4093

Keywords

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Article

Matloub Hussain and Paul R. Drake

The purpose of this paper is to understand the effect of batching on bullwhip effect in a model of multi‐echelon supply chain with information sharing.

Abstract

Purpose

The purpose of this paper is to understand the effect of batching on bullwhip effect in a model of multi‐echelon supply chain with information sharing.

Design/methodology/approach

The model uses the system dynamics and control theoretic concepts of variables, flows and feedback processes and is implemented using iThink® software.

Findings

It has been seen that the relationship between batch size and demand amplification is non‐monotonic. Large batch sizes, that when combined in integer multiples can produce order rates that are close to the actual demand, produce little demand amplification, i.e. it is the size of the remainder of the quotient that is the determinant. It is further noted that the value of information sharing is greatest for smaller batch sizes, for which there is a much greater improvement in the amplification ratio.

Research limitations/implications

Batching is associated with the inventory holding and backlog cost. Therefore, future work should investigate the cost implications of order batching in multi‐echelon supply chains.

Practical implications

This is a contribution to the continuing research into the bullwhip effect, giving supply chain operations managers and designers a practical way into controlling the bullwhip produced by batching across multi‐echelon supply chains.

Originality/value

Previous similar studies have used control theoretic techniques and it has been pointed out that control theorists are unable to solve the lot sizing problem. Therefore, system dynamic simulation has been applied to investigate the impact of various batch sizes on bullwhip effect.

Details

International Journal of Physical Distribution & Logistics Management, vol. 41 no. 10
Type: Research Article
ISSN: 0960-0035

Keywords

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Article

David H. Taylor

The demand amplification effect has been well described in the literature over many years. This paper reports the results of a research project carried out in the UK…

Abstract

The demand amplification effect has been well described in the literature over many years. This paper reports the results of a research project carried out in the UK automotive component supply chain, which set out to eliminate the effect in practice. The paper describes the progression from the identification of demand amplification, through a practical approach for its measurement, to the development of a methodology to overcome the negative impacts of the effect across three echelons of the supply chain. The results of a six‐month trial implementation are reported.

Details

International Journal of Physical Distribution & Logistics Management, vol. 30 no. 6
Type: Research Article
ISSN: 0960-0035

Keywords

Abstract

Details

Structural Models of Wage and Employment Dynamics
Type: Book
ISBN: 978-0-44452-089-0

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Book part

William F. Danaher and Trisha L. Crawshaw

We use framing theory to analyze songs and poetry from the US women’s movement. Specifically, we utilize frame amplification and transformation as concepts to answer the…

Abstract

We use framing theory to analyze songs and poetry from the US women’s movement. Specifically, we utilize frame amplification and transformation as concepts to answer the question: did messages in songs and poetry from the women’s movement change as the movement achieved its original goal of suffrage? Furthermore, are there new organizational goals mentioned in musical artifacts from the second-wave feminist movement? And, if so, why? We find that songs became more radical in the second wave of the women’s movement. This shift reflects and reconstitutes the changing concerns of social movement activists. We demonstrate how frame amplification and transformation are important theoretical concepts in explaining the ideological shifts found in songs and poetry from the first- and second-wave women’s movement.

Details

Bringing Down Divides
Type: Book
ISBN: 978-1-78769-406-4

Keywords

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Article

Zheng Hong and YiHai Zhou

Faced with the financing problem of small-medium enterprises (SMEs), China has attempted to establish as many as third party's collateral institutions. The paper aims to…

Abstract

Purpose

Faced with the financing problem of small-medium enterprises (SMEs), China has attempted to establish as many as third party's collateral institutions. The paper aims to study the design of collateral arrangements including collateral fee rates, risk sharing, collateral capital requirements, types of collateral institutions and recollateral institution, etc.

Design/methodology/approach

The paper extends the model of Holmstrom and Tirole to develop the analytic framework of the theory of financing collateral. From the perspective of contract design, the paper establishes a moral hazard model focusing on the minimum capital requirement of the borrower under the condition of risk neutral and limited liability, while considering the structure of lender-collateral institution-borrower.

Findings

According to the research, only under certain conditions can third party's collateral arrangements tackle the financing problems of SMEs. Diversification, anti-collateral and linked-transactions are three means to improve financing conditions, but the most important way is efficient monitoring by collateral institutions, especially when it has relative advantage over the lender. In order to improve financing conditions of SMEs, China should rely more on efficient monitoring by banks not on excess development of collateral institutions, meanwhile relax rigid collateral supervision policies. Collateral institutions should be industry-specific, association or transaction-related type.

Originality/value

First, from the perspective of contract design, the paper analyzes the comprehensive institutional arrangements of third party's collateral considering mutual relationships of component elements and develops the analytic framework of the theory of third party's collateral, especially points out necessary conditions of its efficient arrangements. Second, the paper studies various efficient financing mechanisms under the institutional arrangements of third party's collateral and focusing on the role of monitoring and monitors, and the paper also has important policy implications, i.e. the paper should develop specific collateral institutions and promote monitoring role of credit institutions.

Details

China Finance Review International, vol. 3 no. 4
Type: Research Article
ISSN: 2044-1398

Keywords

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Article

Manfredi Bruccoleri, Salvatore Cannella and Giulia La Porta

– The purpose of this paper is to explore the effect of inventory record inaccuracy due to behavioral aspects of workers on the order and inventory variance amplification.

Abstract

Purpose

The purpose of this paper is to explore the effect of inventory record inaccuracy due to behavioral aspects of workers on the order and inventory variance amplification.

Design/methodology/approach

The authors adopt a continuous-time analytical approach to describe the effect of inbound throughput on the inventory and order variance amplification due to the workload pressure and arousal of workers. The model is numerically solved through simulation and results are analyzed with statistical general linear model.

Findings

Inventory management policies that usually dampen variance amplification are not effective when inaccuracy is generated due to workers’ behavioral aspects. Specifically, the psychological sensitivity and stability of workers to deal with a given range of operational conditions have a combined and multiplying effect over the amplification of order and inventory variance generated by her/his errors.

Research limitations/implications

The main limitation of the research is that the authors model workers’ behavior by inheriting a well-known theory from psychology that assumes a U-shaped relationship between stress and errors. The authors do not validate this relationship in the specific context of inventory operations.

Practical implications

The paper gives suggestions for managers who are responsible for designing order and inventory policies on how to take into account workers’ behavioral reaction to work pressure.

Originality/value

The logistics management literature does not lack of research works on behavioral decision-making causes of order and inventory variance amplification. Contrarily, this paper investigates a new kind of behavioral issue, namely, the impact of psycho-behavioral aspects of workers on variance amplification.

Details

International Journal of Physical Distribution & Logistics Management, vol. 44 no. 10
Type: Research Article
ISSN: 0960-0035

Keywords

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