Search results

A nanosilica adsorbent was prepared and characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and BET.

The optimum conditions for the highest adsorption performance were determined by kinetic modeling. The adsorbent was used for the adsorption of acetaminophen (ACT), and the parameters affecting the adsorption were discussed like pH, initial concentration, contact time and adsorbent dosage. The adsorbent have been characterized by SEM, XRD and BET analysis. The kinetic models including pseudo-first-order and pseudo-second-order with Langmuir and Freundlich isotherm models were applied to investigate the kinetic and isotherms parameters.

The adsorption of ACT increased to around 95% with the increase of nanosilica concentration to 30 g/L. Moreover, the adsorption process of ACT follows the pseudo-second-order kinetics and the Langmuir isotherm with the maximum adsorption capacity of 609 mg/g.

This study provided a simple and effective way to prepare of nanoadsorbents. This way was conductive to protect environmental and subsequent application for removal of emerging pollutants from aqueous solutions.

The novelty of the study is synthesizing the morphological and structural properties of nanosilica-based adsorbent (specific surface area, pore volume and size, shape and capability) and improving its removal rate through optimizing the synthesis method; and studying the capability of synthesis of nanosilica-based adsorbent for removal of ACT as a main emerging pharmaceutical water contaminant.

The purpose of this study to investigate acetaminophen (ACT) degradation efficiencies by using ozone/persulfate oxidation process in a batch reactor. In addition, the effects of various parameters on the ACT removal efficiency toward pathway inference of ACT degradation were investigated.

The experiments were in the 2 L glass vessels. Ozone gas with flow rate at 70 L.h⁻¹ was produced by ozone generator. After the adjustment of the pH, various dosages of persulfate (1, 3, 5, 7 and 9 mmol.L⁻¹) were then added to the 500 mL ACT-containing solution with 150 mg.L⁻¹ of concentration. Afterward, ozone gas was diffused in glass vessels. The solution after reaction flowed into the storage tank for the detection. The investigated parameters included pH and the amount of ozone and persulfate addition. For comparison of the ACT degradation efficiency, ozone/persulfate, ozone and persulfate oxidation in reactor was carried out. The ACT concentration using a HPLC system equipped with 2998 PDA detector was determined at an absorbance of 242 nm.

ACT degradation percentage by using ozone or persulfate in the process were at 63.7% and 22.3%, respectively, whereas O₃/persulfate oxidation process achieved degradation percentage at 91.4% in 30 min. Degradation efficiency of ACT was affected by different parameter like pH and addition of ozone or persulfate, and highest degradation obtained when pH and concentrations of persulfate and ozone was 10 and 3 mmol.L⁻¹ and 60 mg.L⁻¹, respectively. O₃, OH^• and SO⁴⁻ were evidenced to be the radicals for degradation of ACT through direct and indirect oxidation. Gas chromatography–mass spectrometer analysis showed intermediates including N-(3,4-dihydroxyphenyl) formamide, hydroquinone, benzoic acid, 4-methylbenzene-1,2-diol, 4-aminophenol.

This study provided a simple and effective way for degradation of activated ACT as emerging contaminants from aqueous solution. This way was conducted to protect environment from one of the most important and abundant pharmaceutical and personal care product in aquatic environments.

There are two main innovations. One is that the novel process is performed successfully for pharmaceutical degradation. The other is that the optimized conditions are obtained. In addition, the effects of various parameters on the ACT removal efficiency toward pathway inference of ACT degradation were investigated.

The aim of this paper is to call for an increased focus on the ethics of direct-to-consumer (DTC) prescription drug advertising. This is important, not only to improve DTC prescription drug advertising, but also to inform DTC advertising of future medical advances.

This conceptual paper discusses two examples of medical advances – personal genetic testing services and surgically implanted medical devices – to explain how investigating the research of DTC prescription drug advertising can set the stage for more ethical advertising of future medical advances.

Specific issues related to health literacy, at-risk populations impacted by health disparities, and medicalization of issues common to aging relate to the DTC advertising of prescription drugs and other medical advances. Creative approaches to investigating these issues in the context of prescription drug advertising can enrich the debate about drug advertising, but also prepare researchers, policymakers, and consumers for future advertising of new medical developments.

The value of this paper is its call for increased focus on the ethics of DTC prescription drug advertising, to improve the current marketing environment but also lay the foundation for other healthcare marketing in the future.

Taking an emerging country perspective, this paper aims to investigate consumers’ preferences for over-the-counter (OTC) drugs, regarding three attributes: country-of-origin (COO), brand status (branded versus generic) and price. The second purpose is to test the effect of COO and brand status on consumers’ perceptions of quality, trust and purchasing intentions.

After a preliminary qualitative study, consumers answered a follow-up questionnaire to evaluate eight product combinations (COO/brand status/price) for three categories of OTC drugs. Conjoint analysis allowed assessing the importance of COO compared to brand status and price, while ANOVA was used to test the effect of COO and branding status on consumers’ responses.

Findings show that, in an emerging countries context, COO is less important than brand status in consumers’ preferences. COO and brand status have a greater effect on consumers’ perceptions of drug quality and trust than on purchasing intentions.

The limited number of factors (brand status/COO/price) could have amplified their relative importance.

Pharmaceutical companies from industrialized countries, exporting generic drugs to emerging markets, can benefit from the favorably perceived COO of their drugs and thus help the acceptance of generic drugs in these markets.

The study has two major contributions. It aims to contribute to a better understanding of consumer behavior in the pharmaceutical field. It also transposes the framework on COO to the context of an emerging country: Tunisia.

Executives at biotechnology firm Genzyme are debating funding a clinical trial for a new version of a medical device called Synvisc. The trial is expensive and the odds of success are not high, but the upside is substantial. The case presents a common business question: invest or not? The case forces students to think about customer insights, wrestle with a number of complex issues, and evaluate the financials of the decision.

The case is ideal for teaching financial analysis and decision making. It can also be used to teach marketing, new product strategy, and healthcare industry management.

Few reports considering drug use among earthquake survivors exist. The present study aims to examine the Bam earthquake's impact on prescribing patterns and drug use among residents five years post‐disaster.

In this study, 297,104 prescriptions, issued by general practitioners in Bam city in 2008, were investigated for drugs/prescriptions, drug name, drug category, using WHO appropriate general practice prescribing indicators.

Mean drugs per prescription was 3.1. Drugs affecting the central nervous system were the most frequently used among Bam residents, representing 25.1 per cent, followed by antimicrobials, respiratory, cardiovascular and gastrointestinal tract drugs. Benzodiazepines were the most frequently used central nervous system drugs (15.8 per cent) followed by narcotic analgesics and tricyclic antidepressants. Penicillins (6.4 per cent) and cephalosporines (2.3 per cent) were the most frequently used antimicrobial drugs.

Results emphasize increased drug use for psychological disturbances and the need for strategies to improve mental health among disaster survivors.

This paper deals with the combined management and design of a sustainable pharmaceutical supply chain network with considering recycling.

This paper first utilizes the analytical hierarchy process to select and rank green manufacturers. Second, the authors proposed a multi-objective nonlinear mathematical model to design a sustainable pharmaceutical supply chain network. The proposed model has been linearized and solved using the LP-metric method using GAMS software.

A real case study has been conducted in Iran. The results show that environmental and social issues can be improved while minimizing total costs.

Given the criticality and importance of drugs in human health and the importance of recycling in today's world, proper management and design of a sustainable drug supply chain are necessary. This study pays special attention to environmental issues by utilizing multi-criteria decision approaches and customer satisfaction.

Human health is strongly affected by diet. By the increased use of food industries products, public knowledge about health factors and side effects of chemical additives, the concepts of human health founded an important aspect during past years, and application of natural-based ingredients such as coloring, flavoring, texturizing and anti-oxidative agents was increased.

The aim of the present paper is to review the published scientific research studies about lycopene health benefits in different human disease or disorders and bold the necessity of study the health effects of lycopene after its formulation in food industrial products. About 190 papers were searched in Google Scholar, PubMed, Web of Science databases and 72 relevant papers were used. It was found that in medical studies, the lycopene oleoresin or powder is used directly to the subjects. However, it is necessary to study the effectiveness of lycopene in diet food products.

According to the literature, it has beneficial effects on cancers, glands, reproductive system, bone, gastric system, liver and fat reduction in the body. Also, it was concluded from the literature that lycopene oxidative cleavages make also its chemo protective effects which is a lost key element to study different food processing on lycopene products or its isomers in final food products and on human health.

Many ingredients in food formulations are substituted by natural products. Lycopene is a colorant but also, according to the literature, has a strong antioxidative and anti-inflammatory effect to reduce the risk of most important human disease and disorders. Future research in food science can emphasize the effect of different unit operations or formulations on lycopene effects on human health.

The purpose of this paper is to describe and discuss the limitations of strategies that mothers of undocumented Latino children use in an emerging community to address the health needs of their children.

In-depth interviews with low-income immigrant mothers of undocumented Latino children (n=10) and social service providers (n=6). Interviews were transcribed, coded using Atlas-ti and analyzed to identify common perspectives on the strategies used to secure healthcare for uninsured undocumented children.

Mothers of undocumented Latino children struggle to secure healthcare for their children. Based on the principles of familismo and personalismo, they rely on social support networks such as friends, relatives and fellow churchgoers to secure information about available healthcare options. Despite the willingness of social and health service providers to help them access healthcare, options are limited and depend on the actions of individuals rather than organized solutions. Securing care for undocumented children using families, friends and sympathetic individual providers as the source of information and advice leads to fragile unsustainable solutions.

This paper adds to the small yet growing literature of Latinos in emerging communities.

Emerging Latino communities are usually unprepared to welcome Latinos and address its various needs. Undocumented children are a particularly vulnerable group and any sustainable strategy to address their needs would require structural changes in existing health services to ensure that undocumented children’s lives are not affected by poor health.

Healthcare access problems for immigrant children are presented from the perspective of parents and offers a nuanced description of health systems unpreparedness to provide care for vulnerable groups whose immigrant status is poorly understood.

The purpose of this paper is to analyze the relationship between Latin American migrants and the Spanish healthcare system, from the users’ perspective, in order to examine the socio-cultural determinants for access and attention, as well as the possible difficulties faced when attending institutional facilities.

This work is based on qualitative ethnographic research with the Latin American community established in the region of Castile and León, Spain. Analysis was established through a thematic approach and illustrated with the testimonies of participants involved, to inspect personal meanings and interpretations, as well as specific practices regarding healthcare.

The encounter between foreigners and health services is frequently expressed with negative emotions, such as feelings of fear facing a system that is perceived as designed “for others.” For many Latin American immigrants in Spain, institutional healthcare is not considered their first choice for treating illness. This has been related to economic, bureaucratic, ideological and emotional factors.

Most of the existing literature about immigrant healthcare in Spain has focused on sanitary conditions or patterns of service use from an institutional perspective and a quantitative approach. This paper highlights the perceptions of users to enrich comprehension of the rapport between migrants and medical care.