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Biotech companies stand as key actors in pharmaceutical innovation. The high risk and long timelines inherent with their R&D investments might hinder their access to funding, potentially stifling innovation. This study aims to explore into the appeal of biotech companies to capital market investors, whose financial backing could bolster the growth of the biotechnology sector.

This paper uses a dataset of 774 US publicly listed biotech firms to investigate their risk and return characteristics by comparing them to pharmaceutical firms and a sample of matched non-biotech R&D-intensive firms over the sample period 1980–2021. Tests show that the conclusions remain consistent across diverse methodological approaches.

The paper shows that biotech companies are riskier than the average firm in the market index but outperform on a risk-adjusted basis both the market and a matched group of R&D-intensive firms. This is particularly true for large capitalization biotech, which is also shown to provide a diversification benefit by reducing the downside risk in past crisis periods.

This paper provides insight relevant to the current debate about the overall performance of the biotech industry in terms of policy changes and their impact on small, early-stage biotech firms. While small and early-stage biotech firms are playing an increasing role in scientific innovation, this study confirms their greater vulnerability to financial risks and the importance of access to capital markets in enabling those companies to survive and evolve into larger biotech.

The use of technology in 4th industrial revolution is at its peak. Industries are trying to reduce the consumption of resources by effectively utilizing information and technology to connect different functioning agents of the manufacturing industry. Without digitization “Industry 4.0” will be a virtual reality. The present survey-based study explores the factual status of digital manufacturing in the Northern India.

After an extensive literature review, a questionnaire was designed to gather different viewpoints of Indian industrial practitioners. The first half contains questions related to north Indian demographic factors which may affect digitalization of India. The latter half includes the queries concerned with various operational factors (or drivers) driving the digital revolution without ignoring Indian constraints.

The focus of this survey was to understand the current level of digital revolution under the ongoing push by the Indian government focused upon digital movement. The analysis included non-parametric testing of the various demographic and functional factors impacting the digital echoes, specifically in Northern India. Findings such as technological upgradations were independent of type of industry, the turnover or the location. About 10 key operational factors were thoughtfully grouped into three major categories—internal Research and Development (R&D), the capability of the supply chain and the capacity to adapt to the market. These factors were then examined to understand how they contribute to digital manufacturing, utilizing an appropriate ordinal logistic regression. The resulting predictive analysis provides seldom-seen insights and valuable suggestions for the most effective deployment of digitalization in Indian industries.

The country-specific Industry 4.0 literature is quite limited. The survey mainly focuses on the National Capital Region. The number of demographic and functional factors can further be incorporated. Moreover, an addition of factors related to ecology, environment and society can make the study more insightful.

The present work provides valuable insights about the current status of digitization and expects to facilitate public or private policymakers to implement digital technologies in India with less efforts and the least resistance. It empowers India towards Industry 4.0 based tools and techniques and creates new socio-economic dimensions for the sustainable development.

The quantitative nature of the study and its statistical predictions (data-based) are novel. The clubbing of similar success factors to avoid inter-collinearity and complexity is seldom seen. The predictive analytics provided in this study is quite elusive as it provides directions with logic. It will help the Indian Government and industrial strategists to plan and perform their interventions accordingly.

Innovation management in the healthcare sector has undergone significant evolutions over the last decades. These evolutions have been investigated from a variety of perspectives: clusters, ecosystems of innovation, digital ecosystems and regional ecosystems, but the dynamics of networks have seldom been analyzed under the lenses of entrepreneurial ecosystems (EEs). As identified by Cao and Shi (2020), the literature is silent about the organization of resource allocation systems for network orchestration in EEs. This article investigates these elements in the healthcare sector. It discusses the strategic role played by entrepreneurial support organizations (ESOs) in resource allocation and elaborates on the distinction between sponsored and nonsponsored ESOs in EEs. ESOs are active in network orchestration. The literature explains that ESOs lift organizational, institutional and cultural barriers, and support entrepreneurs' access to cognitive and technological resources. However, allocation models are not yet discussed. Therefore, our research questions are as follows: What is the resource allocation model in healthcare-related EEs? What is the role played by sponsored and nonsponsored ESOs as regards resource allocation to support the emergence and development of EEs in the healthcare sector?

The article offers an explanatory, exploratory, and theory-building investigation. The research design offers an abductive research protocol and multi-level analysis of seven (sponsored and nonsponsored) ESOs active in French healthcare ecosystems. Field research elaborates on semi-structured interviews collected between 2016 and 2022.

This article shows explicit complementarities between top-down and bottom-up resource allocation approaches supported by ESOs in the healthcare sector. Despite explicit originalities in each approach, no network orchestration model prevails. Multi-polar coordination is the rule. Entrepreneurs' access to critical technological and cognitive resources is based on resource allocation modalities that differ for sponsored versus nonsponsored ESOs. Emerging from field research, this research also shows that sponsored and nonsponsored ESOs manage their roles in different ways because they confront original issues about organizational legitimacy.

Beyond the results listed above, the main originalities of the paper relate to the instantiation of multi-level analysis operated during field research and to the confrontation between sponsored versus nonsponsored ESOs in the domain of healthcare-related innovation management. This research shows that ESOs have practical relevance because they build original routes for resource allocation and network orchestration in EEs. Each ESO category (sponsored versus nonsponsored) provides original support for resource allocation. The ESO's legitimacy is inferred either from the sponsor or the services delivered to end-users. This research leads to propositions for future research and recommendations for practitioners: ESO managers, entrepreneurs, and policymakers.

The pandemic has brought to light the importance of quickly adopting new technologies and building resilient organisations. Also, the Sustainable Development Goals (SDGs) can be addressed in large part through technological innovations. The development of smart systems which are linked with the Internet of Things (IoT) can create different opportunities to strategically face the barriers linked with the SDGs and make sure that there is an environmentally sustainable, equitable and healthy society. This study has utilised secondary and qualitative data and has adopted the interpretative and deductive approaches. It has given significance to several aspects of the SDGs and has linked them with digital technology such as accessibility to safe and clean portable water, production of sustainable food along with the generation of green energy and its utilisation. This study has evaluated the advantages of digitalisation so that it can catalyse the transition towards SDGs and improve the health of the citizens by giving digital accessibility specifically to the underserved community. The research has selected the most essential themes which are linked to the context of SDGs and has deeply evaluated a lot of information obtained from authentic secondary resources. At last, it provides a conclusion and recommendations where it has suggested several initiatives which could be made for enhancing the overall scenario and has also disguised the limitations that were identified while completing the study.

Tourism is considered one of the globe's most prominent sectors, generating considerable forex revenues and employment generation, contributing to world peace and solidarity among many nations. However, it is negatively influenced by different factors like the spread of diseases, terrorist attacks, outbreaks of war, etc. The COVID-19 pandemic triggered unforeseen upheavals, resulting in demand and supply uncertainties in nearly every area of the economy (El-Erian, 2020). Thus, it is relevant to study the impact of the pandemic on the tourism industry. This chapter explains the journey of tourism during the COVID-19 pandemic by portraying the status of global tourism, how it impacted the Indian economy and its revival strategies, with special mention to Kerala tourism. The pandemic also resulted in a considerable change in the travel intentions of tourists, their travel preferences and their attitude towards travel. Hence, this chapter also presents the changed travel intentions of tourists that will help the industry players modify their products per the tourist's expectations. Finally, this chapter presents how the tourism industry recovered from the pandemic from both the supplier and demand perspectives, which will be helpful for all tourism stakeholders.

Numerous biotechnology and pharmaceutical firms have undergone considerable changes and adapted to the challenge of developing sustainable products and services. However, few studies have explored the factors that contribute to the success of external innovation and value co-creation strategies adopted by biotechnology and pharmaceutical firms. The purpose of this study is to examine how biotechnology and pharmaceutical industries use value co-creation strategies to obtain external resources.

This study developed a conceptual framework based on the relevant literature. The study applied a resource-based approach, dynamic capability theory and a qualitative multiple-case study design to investigate several research questions; semi-structured interviews were conducted with representatives from 11 biotechnology/pharmaceutical firms in Taiwan, and the data extracted from the interview content were axially coded.

This study revealed that factors such as dynamic marketing capabilities and process optimization contributed to the success of the aforementioned strategies; several propositions were also developed on the basis of the literature review and coded data, thereby providing insights regarding the relative efficacy and propriety of various external innovation and value co-creation strategies and models in various situations and contexts. Firms and technology providers might enter a technology licensing agreement, establish a joint venture company; participate in a merger/acquisition depending on their size, research and development capabilities; or goals and time- and cost-related factors.

The main original contributions of this study are the proposed conceptual framework and the insights provided regarding the relative efficacy and propriety of different external innovation and value co-creation strategies and models in different situations and contexts.

In this case study, we examine how a citrus peel valorising company based in the Netherlands was able to adopt a circular business model while navigating regulatory, managerial, and supply chain-related barriers.

In-depth, semi-structured interviews with key personnel in the company, notes from field observations, photographs of the production process, and documents from a legal judgement served as data for this single, qualitative case study. Data were coded inductively using the in vivo technique and were further developed into four themes and a case description.

Results from our study indicate that the regulatory and political contexts in the Netherlands were critical to the company’s success. Like in the case of most fruitful industrial symbioses, partnerships founded on mutual trust and economically appealing value propositions played a crucial role in ensuring commercial viability. Collaborating with larger corporations and maintaining transparent communication with stakeholders were also significant contributing factors. Lastly, employees’ outlook towards circularity combined with their willingness to learn new skills were important driving factors as well.

In addition to expanding the scholarship on the adoption of circular business models, this research offers novel insights to policymakers and practitioners. It provides empirical evidence regarding the importance of public awareness, adaptable legislation, and harmonised policy goals for supporting sustainable entrepreneurship in the circular economy.

Customers today expect businesses to cater to their individual needs by tailoring the products they purchase to their own preferences. The term “Industry 5.0” refers to a new wave of manufacturing that aims to meet each customer's unique demands. Even while Industry 4.0 allowed for mass customization, that wasn't good enough before, customers today demand individualized products at scale, and Industry 5.0 is driving the transition from mass customization to mass personalization to meet these demands. It caters to the individual needs of each consumer by meeting their demands. More specialized components for use in medicine are made possible by the widespread customization made possible by Industry 5.0. These individualized parts are included into the medical care of the patient to meet their specific needs and preferences. In the current medical revolution, an enabling technology of Industry 5.0 can produce medical implants, artificial organs, bodily fluids, and transplants with pinpoint accuracy. With the advent of AI-enabled sensors, we now live in a world where data can be swiftly analyzed. Machines may be programmed to make complex choices on the fly. In the medical field, these innovations allow for exact measurement and monitoring of human body variables according to the individual's needs. They aid in monitoring the body's response to training for peak performance. It allows for the digital dissemination of accurate healthcare data networks. In order to collect and exchange relevant patient data, every equipment is online.