Electrochemical Sensors in Bioanalysis

Citation

Stefan, R., van Staden, F. and Aboul‐Eniein, H.Y. (2002), "Electrochemical Sensors in Bioanalysis", Sensor Review, Vol. 22 No. 4, pp. 363-363. https://doi.org/10.1108/sr.2002.22.4.363.1

Electrochemical Sensors in Bioanalysis provides a concise review of the latest methods and materials used to produce electrochemical sensors. Comprising 15 chapters, this informative reference text reads more like a technical dictionary than a textbook.

Chapter 1 introduces “Electrochemical sensor design” and addresses design considerations for solid and liquid membrane electrodes; modified paste electrodes; gas sensors; biosensors; immunosensors; sensor arrays; and microelectrodes. “New theoretical concepts for ion‐selective membrane electrodes” are presented in chapter 2 and includes discussion of the configuration of membrane‐sol interface; charge transfer across the membrane‐solution interface; and the main types of equilibria which are taking place at the membrane‐solution interface.

“Response characteristics of electrochemical sensors” are discussed in chapter 3, while chapter 4 presents “Analytical methods that use electrochemical sensors”. The following two chapters discuss “Applications of electrochemical sensors in the analysis on inorganic substances”, and “Applications of electrochemical sensors in the analysis of organic substances”, respectively.

Chapter 7, “The assay of DNA using electrochemical sensors”, presents biosensors and electron transfer‐electrochemical sensors for the assay of DNA. “Electrochemical sensors used in the diagnosis of HIV”, and “Enantioselective electrochemical sensors” are introduced in chapters 8 and 9, respectively. Subjects addressed include ion‐selective membrane electrodes, biosensors and immunosensors utilised for the qualification of HIV degree of infection; molecular recognition of chiral discrimination; and applications of enantioselective electrochemical sensors in bioanalysis.

The following three chapters discuss microbial sensors, electrochemical sensor arrays, and the utilisation of microelectronics for in vivo and in vitro analysis.

Flow injections analysis (FIA), sequencial injection analysis (SIA), and the role of electrochemical sensors as detectors in flow systems, are amongst the topics presented in chapter 13, “Flow systems with electrochemical sensors as detectors”. The two final chapters of the book discuss “Validation criteria for developing electrochemical sensors applied for bioanalysis”, and “Estimation of uncertainties for electrochemical sensors applied in bioanalysis”.

This book is suitable for researchers and academics in the fields of analytical chemistry, biology, physics, microelectronics and medicine.