Emerald Group Publishing Limited
Copyright © 2011, Emerald Group Publishing Limited
Article Type: Food facts From: Nutrition & Food Science, Volume 41, Issue 4
Light has been cast on the interaction between broccoli consumption and reduced prostate cancer risk. Researchers at IFR led by Professor Richard Mithen, writing in BioMed Central’s open access Journal Molecular Cancer have found that sulforaphane, a chemical found in broccoli, interacts with cells lacking a gene called PTEN to reduce the chances of prostate cancer developing.
The research team found that in cells which express PTEN, dietary intervention with sulforaphane has no effect on the development of cancer. In cells that do not express the gene, however, sulforaphane causes them to become less competitive, providing an explanation of how consuming broccoli can reduce the risk of prostate cancer incidence and progression.