It is remarkable how few cases in any outbreak are attended by a fatal issue, and pathological data from post‐mortem examinations are correspondingly meagre. The clinical symptoms point to the upper intestinal tract as the area most affected, and this is in accordance with the findings at necropsy. The severe vomiting and purging must remove much of the unabsorbed toxic material within the alimentary canal, and the rapid recovery in many cases is presumably the beneficial result of these excretory processes. It would be expected that the cases presenting evidence of infection with living organisms would show more prolonged symptoms than in those in which only toxins are present, but in most cases recovery occurs rapidly, and evidence of invasion of the blood stream by organisms is seldom obtained. Nevertheless, the development of aggultinins to salmonella organisms is frequently reported, even in cases in which toxins only are supposed to have been present. As it is the general experience of bacteriologists that it is extremely difficult to produce antibodies in the blood of animals by administering organisms by the alimentary tract, and is only partially successful when enormous doses are given, and frequently only after starvation or in association with the feeding of agents which interfere with normal digestion, this finding of aggultinins in the blood of food‐poisoning cases is the more remarkable and worthy of fuller investigation on experimental lines.
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