Intensive glucose lowering treatment and all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes

Citation

(2012), "Intensive glucose lowering treatment and all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes", Clinical Governance: An International Journal, Vol. 17 No. 1. https://doi.org/10.1108/cgij.2012.24817aaa.009

Intensive glucose lowering treatment and all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes

Intensive glucose lowering treatment and all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 17, Issue 1

Boussaageon, R., Bejan-Angoulvant, T., Saadatian-Elahi, M., Lafont, S., Bergeonneau, C., Kassai, B., Erpeldinger, S., Wright, J.M., Gueyffier, F. and Cornu, C.,Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials,BMJ,2011,p. 343

This review concluded that the benefits of intensive glucose lowering treatment were limited: a 19 per cent increase in all-cause death and a 43 per cent increase in cardiovascular death could not be ruled out. The benefit to risk ratio in the prevention of vascular events remained uncertain. Given the limitations of the included studies and the analysis undertaken, the authors’ cautious conclusions seem appropriate.