Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data

Citation

(2008), "Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data", Clinical Governance: An International Journal, Vol. 13 No. 2. https://doi.org/10.1108/cgij.2008.24813bae.007

Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 13, Issue 2.

L.M. Askie, L. Duley, D.J. Henderson-Smart and L.A. StewartLancet2007Vol. 369pp. 1791-98

This review of individual patient data evaluated the efficacy of antiplatelet agents for the primary prevention of pre-eclampsia. Antiplatelet agent prophylaxis reduced the risk of pre-eclampsia, pre-term birth before 34 weeks’ gestation and serious adverse outcomes of pregnancy, without increasing the rate of bleeding events. The review has no major flaws and the conclusions are likely to be reliable.