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Emerald Group Publishing Limited
Copyright © 2008, Emerald Group Publishing Limited
Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 13, Issue 2.
Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stentsA. Kastrati, J. Mehilli, J. Pache, C. Kaiser, M. Valgimigli, H. Kelbaek, M. Menichelli, M. Sabate, M.J. Suttorp, D. Baumgart, M. Seyfarth, M.E. Pfisterer and A. SchomigNew England Journal of Medicine2007Vol. 356pp. 1030-39
This well-conducted review using individual patient data compared the long-term effects of sirolimus-eluting stents and bare-metal stents in people with coronary artery disease. The authors found no difference in overall long-term survival or survival free of myocardial infarction between the two stents. The need for reintervention was reduced with sirolimus-eluting stents, but the risk of thrombosis was no less. These conclusions are likely to be reliable.