Combined aspirin-oral anticoagulant therapy for cardiovascular disease

Citation

(2008), "Combined aspirin-oral anticoagulant therapy for cardiovascular disease", Clinical Governance: An International Journal, Vol. 13 No. 1. https://doi.org/10.1108/cgij.2008.24813aae.007

Combined aspirin-oral anticoagulant therapy for cardiovascular disease

DARE SummariesCombined aspirin-oral anticoagulant therapy for cardiovascular diseaseF. Dentali, J.D. Douketis, W. Lim and M. CrowtherArchives of Internal Medicine2007Vol. 167pp. 117-24

This well-conducted review compared the effectiveness and safety of oral anticoagulant (OAC) therapy plus aspirin with OAC alone. The authors concluded that, except for patients with a mechanical heart valve, the benefits of OAC therapy plus aspirin in reducing thromboembolic events were unclear and there were increased risks of major bleeding. This conclusion is likely to be reliable.