Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: meta-analysis of randomized trials

Clinical Governance: An International Journal

ISSN: 1477-7274

Article publication date: 23 October 2007

83

Citation

(2007), "Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: meta-analysis of randomized trials", Clinical Governance: An International Journal, Vol. 12 No. 4. https://doi.org/10.1108/cgij.2007.24812dae.005

Publisher

:

Emerald Group Publishing Limited

Copyright © 2007, Emerald Group Publishing Limited


Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: meta-analysis of randomized trials

Summaries of abstracts from Database of Abstracts of Reviews of Effectiveness (DARE)

About DARE

Systematic reviews provide reliable information about what is known and not known about the effects of interventions. But just as with individual studies, systematic reviews can be hard to find, may have methodological flaws and can be difficult to interpret. Database of Abstracts of Reviews of Effectiveness (DARE) provides the solution by systematically identifying and quality assessing reviews from around the world. For each included review an abstract is written that describes the review, including the methods, results and conclusions, together with a critical commentary on the overall quality of the review. DARE contains over 4,000 abstracts of systematic reviews that have been quality-assessed and critically appraised on a broad range of health and social care related topics. The database also includes abstracts of all Cochrane reviews and protocols. The database is produced by the Centre for Reviews and Dissemination (CRD), and is publicly available free of charge via the web. The web interface now provides enhanced search facilities and a clearer layout. DARE on the web is updated every month and contains details of abstracts in the process of being written. These can be “fast-tracked” on request. The database can now be accessed at www.crd.york.ac.uk

DARE Summaries

Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: meta-analysis of randomized trials

C. Stettler, S. Allemann, P. Juni, C.A. Cull, R.R. Holman, M. Egger, S. Krahenbuhl, P. DiemAmerican Heart Journal2006Vol. 152pp. 27-38

This well-conducted systematic review determined the efficacy of improved long-term glycaemic control on macrovascular disease in diabetes mellitus. The authors’ conclusion, that attempts to improve glycaemic control reduced the incidence of macrovascular complications in types 1 and 2 diabetes, is likely to be reliable, although applicability to other populations (i.e. elderly patients and patients with longer duration of diabetes) is questionable, as the authors acknowledged.

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