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A study on the thermal responsive behavior of hydrogel-based materials and their potential use in medical applications

Aniqa Junaid (Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology, Islamabad, Pakistan)
Murtaza Najabat Ali (Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology, Islamabad, Pakistan)
Mariam Mir (Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology, Islamabad, Pakistan)
Sadia Hassan (Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology, Islamabad, Pakistan)

Sensor Review

ISSN: 0260-2288

Article publication date: 11 October 2022

Issue publication date: 18 November 2022

119

Abstract

Purpose

The purpose of this paper is to present synthesis protocol of hydrogel composed of Chitosan (CS) and Poly(ethylene glycol) (PEG) and establish an understanding of its thermal responsive behavior. It aims to prove the basic temperature sensing ability of a novel CS-PEG-based hydrogel and define its sensing span.

Design/methodology/approach

This study includes synthesis of CS and PEG-based hydrogel samples by first performing dissolution of both constituents, respectively, and then adding Glutaraldehyde as the cross-linking agent. It further includes proposed hydrogel’s swelling studies and dynamic behavior testing, followed by hydrogel characterization by Fourier transform infrared spectroscopy, X-ray diffraction and SEM. The last section focuses on the use of proposed hydrogel as a temperature sensor.

Findings

Detailed experimental results show that a hydrogel comprising of CS and PEG presents a thermally responsive behavior. It offers potential to be used as a temperature responsive hydrogel-based sensor which could be used in medical applications.

Originality/value

This research study presents scope for future research in the field of thermally responsive bio-sensors. It provides basis for the fabrication of a thermal responsive sensor system based on hydrogels that can be used in specific medical applications.

Keywords

Acknowledgements

Acknowledgments: No individual other than the authors contributed or provided technical help in this research work.

Funding Statement: There was no financial support for this research work.

Conflict of Interest: The authors have no conflict of interest to declare.

Citation

Junaid, A., Najabat Ali, M., Mir, M. and Hassan, S. (2022), "A study on the thermal responsive behavior of hydrogel-based materials and their potential use in medical applications", Sensor Review, Vol. 42 No. 6, pp. 657-668. https://doi.org/10.1108/SR-10-2021-0366

Publisher

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Emerald Publishing Limited

Copyright © 2022, Emerald Publishing Limited

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