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The latest trend in nano-bio sensor signal analysis

Yijun Teh (School of Microelectronic Engineering, Universiti Malaysia Perlis, Arau, Malaysia)
Asral Bahari Jambek (School of Microelectronic Engineering, Universiti Malaysia Perlis, Arau, Malaysia)
Uda Hashim (Nano Structure Lab on Chip Research Group, Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, Perlis, Malaysia)

Sensor Review

ISSN: 0260-2288

Article publication date: 20 June 2016



This paper aims to discuss a nanoscale biosensor and its signal analysis algorithms.


In this work, five nanoscale biosensors are reviewed, namely, silicon nanowire field-effect-transistor biosensors, polysilicon nanogap capacitive biosensors, nanotube amperometric biosensors, gold nanoparticle-based electrochemical biosensors and quantum dot-based electrochemical biosensors.


Each biosensor produces a different output signal depending on its electrical characteristics. Five signal analysers are studied, with most of the existing signal analyser analyses based on the amplitude of the signal. Based on the analysis, auto-threshold peak detection is proposed for further work.


Suitability of the signal processing algorithm to be applied to nano-biosensors was reported.



This research was supported by the Fundamental Research Grant Scheme, Ministry of Higher Education, Malaysia (FRGS Phase 1, 2014).


Teh, Y., Bahari Jambek, A. and Hashim, U. (2016), "The latest trend in nano-bio sensor signal analysis", Sensor Review, Vol. 36 No. 3, pp. 303-311.



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