TY  - JOUR
AB  - Purpose Extrusion-based additive manufacturing (AM) has been considered as a promising technique to fabricate scaffolds for tissue engineering due to affordability, versatility and ability to print porous structures. The reliability and controllability of the printing process are necessary to produce 3D-printed scaffolds with desired properties and depend on the geometric characteristics such as porosity and pore diameter. The purpose of this study is to develop an analytical model and explore its effectiveness in the prediction of geometric characteristics of 3D-printed scaffolds.Design/methodology/approach An analytical model was developed to simulate the geometric characteristics of scaffolds produced by extrusion-based AM using fluid mechanics. Polycaprolactone (PCL) was chosen as a scaffold material and was assumed to be a non-Newtonian fluid for the model. The effectiveness of the model was verified through comparison with the experimental results.Findings A comparison study between simulation and experimental results shows that strut diameter, pore size and porosity of scaffolds can be predicted by using extrusion pressure, temperature, nozzle diameter, nozzle length and printing speed. Simulation results demonstrate that geometric characteristics have a strong relationship with processing parameters, and the model developed in this study can be used for predicting the scaffold properties for the extrusion-based 3D bioprinting process.Originality/value The present study provides a prediction model that can simulate the printing process by a simple input of processing parameters. The geometric characteristics can be predicted prior to the experimental verification, and such prediction will reduce the process time and effort when a new material or method is applied.
VL  - 26
IS  - 2
SN  - 1355-2546
DO  - 10.1108/RPJ-08-2018-0219
UR  - https://doi.org/10.1108/RPJ-08-2018-0219
AU  - Lee Jiwoon
AU  - Walker Jesse
AU  - Natarajan Sanjay
AU  - Yi Sung
PY  - 2019
Y1  - 2019/01/01
TI  - Prediction of geometric characteristics in polycaprolactone (PCL) scaffolds produced by extrusion-based additive manufacturing technique for tissue engineering
T2  - Rapid Prototyping Journal
PB  - Emerald Publishing Limited
SP  - 238
EP  - 248
Y2  - 2024/05/07
ER  -