TY  - JOUR
AB  - Purpose This study aims to develop a multi-material stereolithography (MMSL) technique to directly fabricate a biphasic osteochondral scaffold.Design/methodology/approach A bespoke prototype MMSL system was developed based on a bottom-up mask projection approach. The system was controlled by a multi-material fabrication algorithm with minimum number of switching cycles during fabrication. A variable-power light source was used to fabricate materials with significantly different curing characteristics. The light-curable poly(ethylene glycol) diacrylate (PEGDA) hydrogel and beta-tricalcium phosphate (β-TCP) ceramic suspension were used for fabricating the biphasic osteochondral scaffold.Findings The bonding strength of the multi-material interface is shown to be mainly affected by the type of photopolymer, rather than the switching of the materials in MMSL. Lighting power densities of 2.64 and 14.98 mW/cm2 were used for curing the PEGDA hydrogel and the ß-TCP ceramic suspension, respectively. A biphasic osteochondral scaffold with complex interface was successfully fabricated.Originality/value This study proposes a potential technical method (MMSL) for manufacturing a complex biphasic osteochondral scaffold composing a PEGDA hydrogel/ß-TCP ceramic composite in a time-efficient and precise manner. The designed bone-cartilage scaffold interface and the surface of the cartilage scaffold can be precisely manufactured.
VL  - 25
IS  - 2
SN  - 1355-2546
DO  - 10.1108/RPJ-07-2017-0144
UR  - https://doi.org/10.1108/RPJ-07-2017-0144
AU  - Wu Xiangquan
AU  - Lian Qin
AU  - Li Dichen
AU  - Jin Zhongmin
PY  - 2018
Y1  - 2018/01/01
TI  - Biphasic osteochondral scaffold fabrication using multi-material mask projection stereolithography
T2  - Rapid Prototyping Journal
PB  - Emerald Publishing Limited
SP  - 277
EP  - 288
Y2  - 2024/04/19
ER  -