The effects of sesame oil consumption on fatigue and mental health status in women with nonalcoholic fatty liver disease: a randomized, double-blinded, controlled trial
ISSN: 0034-6659
Article publication date: 16 May 2023
Issue publication date: 18 October 2023
Abstract
Purpose
This paper aims to examine the effect of sesame oil (SO) on fatigue and mental health status in women with nonalcoholic fatty liver disease (NAFLD) undergoing a weight-loss diet.
Design/methodology/approach
In total, 60 women with NAFLD were randomly assigned to receive 30 g/day of either SO (n = 30) or sunflower oil (n = 30). All the patients received a hypocaloric diet (−500 kcal/day) for 12 weeks in a double-blinded controlled trial. Anthropometric indices, dietary intake, physical activity, fatigue and mental health status were measured at the baseline and the trial cessation.
Findings
In total, 53 participants completed the intervention. Significant reductions in anthropometric indices were observed in both groups (p-value = 0.001). Following SO, fatigue (p-value = 0.002), anxiety (p-value = 0.011) and depression (p-value = 0.013) scores were significantly reduced, while no significant changes were observed in stress scores.
Originality/value
In summary, the present study was conducted to assess the efficacy of SO consumption on fatigue and mental health status among patients with NAFLD. The results revealed SO consumption significantly reduced fatigue, anxiety and depression scores in comparison with the control group, but not for stress scores. Further clinical trials, different doses, with a longer duration of intervention, in different groups, are necessary to confirm the veracity of the results.
Keywords
Acknowledgements
This study was extracted from a PhD dissertation, which was approved by the School of Nutrition and Food Science, Isfahan University of Medical Sciences (code: IR.MUI.RESEARCH.REC.1399.548).
Disclosure statement: No potential competing interest was reported by the authors.
Funding sources: This work was supported by the Isfahan University of Medical Sciences under Grant number 399632.
Ethical statements:
Conflict of interest: There are no relevant financial or nonfinancial competing interests to report.
Ethical review: This study involves human testing and it was approved by the Institutional Review Board of Isfahan University of Medical Sciences (code: IR.MUI.RESEARCH.REC.1399.548).
Informed consent: Written informed consent was obtained from all study participants.
Availability of data and materials: The data sets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Authors’ contributions: All authors have made substantial contributions to the following:
Masoumeh Atefi. Data acquisition, drafting the article or revising it and final approval of the version to be submitted; analysis and interpretation of data.
Mohammad Hassan Entezari. The conception and design of the study.
Hamid Vahedi. Data acquisition, drafting the article or revising it and final approval of the version to be submitted.
Citation
Atefi, M., Entezari, M.H. and Vahedi, H. (2023), "The effects of sesame oil consumption on fatigue and mental health status in women with nonalcoholic fatty liver disease: a randomized, double-blinded, controlled trial", Nutrition & Food Science, Vol. 53 No. 7, pp. 1207-1224. https://doi.org/10.1108/NFS-12-2022-0407
Publisher
:Emerald Publishing Limited
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