The purpose of the study was to evaluate the acute effect of milk proteins supplementation, compared to another nitrogen compound on muscle protein synthesis.
The search was conducted on MEDLINE® (via PUBMED®), Cochrane and Embase databases, using the terms “whey proteins,” “caseins,” “milk proteins,” “protein biosynthesis,” “human” and its related entry terms. The selected outcome was fractional synthetic rate (FSR) before (0) and 3 h after consumption of milk proteins, compared to supplementation with other protein sources or isolated amino acids.
The results were expressed as mean difference (MD) of absolute values between treatments with confidence interval (CI) of 95 per cent. Of the 1,913 identified studies, 4 were included, with a total of 74 participants. Milk proteins generated a greater FSR (MD 0.03 per cent/h, CI 95 per cent 0.02-0.04; p < 0.00001), compared to control group. Acute consumption of milk proteins promotes higher increase in FSR than other protein sources or isolated amino acids.
This paper is a systematic review of the effects of milk proteins supplementation, which is considered an important subject because of its large consumption among athletes and physical exercise practitioners.
This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors. Milena Casagranda was responsible for conceptualization, validation, investigation, data curation, writing and visualization. Priscila Berti Zanella was responsible for conceptualization, validation, investigation, writing and visualization. Alexandra Ferreira Vieira was responsible for conceptualization, formal analysis, review and supervision. Rodrigo Cauduro Oliveira Macedo was responsible for conceptualization, methodology, validation, project administration, review and supervision. The authors declare that there are no conflicts of interest and approve the article.
Casagranda, M., Zanella, P.B., Vieira, A.F. and Macedo, R.C.O. (2019), "Effects of milk proteins supplementation on muscle protein synthesis: A systematic review with meta-analysis", Nutrition & Food Science, Vol. 49 No. 6, pp. 1275-1286. https://doi.org/10.1108/NFS-11-2018-0328
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