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Probiotic soy beverages: a functional beverage on lipid profile, oxidative stress and kidney function: a systematic review of randomized controlled trials

Shakila Ansari (Department of Community Nutrition, Nutrition and Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran)
Mohadeseh Abdi (Department of Community Nutrition, Nutrition and Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran)
Pardis Khalili (Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Sahar Saraf-Bank (Department of Community Nutrition, Nutrition and Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran)

Nutrition & Food Science

ISSN: 0034-6659

Article publication date: 12 August 2024

10

Abstract

Purpose

Probiotic coadministration with soy beverages has been shown to have favorable results in human health. This study aims to conduct a systematic review of randomized clinical trials to examine the effect of probiotic soy beverages (PSB) on human health aspects such as lipid profile, oxidative stress and kidney function.

Design/methodology/approach

The study was conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Relevant articles were extracted from PubMed, SCOPUS, Web of Science, Science Direct and Google Scholar up to April 2024. This paper searched all databases using the following keywords: (“Soy milk” OR “Soy beverage” OR “Fermented soy milk” OR “Soy Fermented Beverages”) AND (“Probiotic” OR “Probiotics”). The literature search did not consider language, age and publication date restrictions.

Findings

A total of 2,183 subjects were included in this review. PSB beneficially decreased low-density lipoprotein cholesterol and total cholesterol levels and increased high-density lipoprotein cholesterol. PSB beneficially affected superoxide dismutase, glutathione peroxidase, glutathione reductase and glutathione. PSB decreased serum creatinine and increased estimated glomerular filtration rate. Cystatin-C and progranulin decreased significantly in the PSB group. PSB had no significant effect on anthropometric indices, while decreased systolic and diastolic blood pressure.

Originality/value

This study provides a brief overview of the effect of PSB on lipid profile, oxidative stress, inflammation and kidney function for the first time.

Keywords

Acknowledgements

Funding: The financial support for conception, design, data analysis and manuscript drafting comes from Isfahan University of Medical Sciences, Isfahan, Iran (no. 2401300).

Citation

Ansari, S., Abdi, M., Khalili, P. and Saraf-Bank, S. (2024), "Probiotic soy beverages: a functional beverage on lipid profile, oxidative stress and kidney function: a systematic review of randomized controlled trials", Nutrition & Food Science, Vol. ahead-of-print No. ahead-of-print. https://doi.org/10.1108/NFS-02-2024-0052

Publisher

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Emerald Publishing Limited

Copyright © 2024, Emerald Publishing Limited

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