Food-derived antioxidants intake association with serum oxidative stress markers and lung infection symptoms in COVID-19 infectious angina patients
ISSN: 0034-6659
Article publication date: 28 August 2024
Issue publication date: 11 September 2024
Abstract
Purpose
Research indicated that dietary antioxidants could improve immune system performance. This study aims to investigate the association of COVID-19 symptoms, total antioxidant capacity and serum inflammatory markers, with dietary antioxidants intake among angina patients.
Design/methodology/approach
A food frequency questionnaire was used in a cross-sectional study among 135 angina patients with COVID-19, to assess dietary antioxidants consumption. Serum levels of tumor necrosis factor, interleukin 1ß, malondialdehyde, high-sensitivity C-reactive protein and total antioxidant capacity were measured by enzyme-linked immunosorbent assay methods.
Findings
Among study angina patients, 76.67% followed unhealthy food patterns and 23.33% followed anti-inflammatory dietary patterns before hospitalization. The angina patients with anti-inflammatory food pattern had less fever (p = 0.021), cough (p = 0.018), dyspnea (p = 0.024), diarrhea (p = 0.014) and pneumonia severity index (p = 0.014) compared to patients with unhealthy food pattern. The serum levels of tumor necrosis factor, interleukin 1ß, high-sensitivity C-reactive protein and malondialdehyde, had a significantly negative association with dietary antioxidants intake (p < 0.05).
Originality/value
There are significant association between antioxidant intake with serum inflammation markers in COVID-19 patients. There is a need for more clinical trial studies for approval of these results.
Keywords
Acknowledgements
The authors extend their gratitude to the university and express appreciation to all patients who participated in the study.
Funding: The research did not receive external funding.
Institutional review board statement: The study was conducted in compliance with the Declaration of Helsinki guidelines. The Ethics Committee of the University approved the study on January 17, 2022.
Informed consent statement: Informed consent was obtained from all study participants, and written consent has been secured from the patients for the publication of this paper.
Data availability statement: Due to privacy and ethical considerations, data availability is restricted.
Conflicts of interest: The authors declare no conflicts of interest.
Citation
Mohajeri, M. and Aghapoor, B. (2024), "Food-derived antioxidants intake association with serum oxidative stress markers and lung infection symptoms in COVID-19 infectious angina patients", Nutrition & Food Science, Vol. 54 No. 7, pp. 1322-1334. https://doi.org/10.1108/NFS-01-2024-0010
Publisher
:Emerald Publishing Limited
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