Dietary intake of energy and fiber in MS patients; an approach to prebiotics role

Amir Reza Moravejolahkami (Department of Clinical Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran)
Zamzam Paknahad (Clinical Nutrition Departmento, Isfahan University of Medical Sciences, Isfahan, Iran)
Ahmad Chitsaz (Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran)

Nutrition & Food Science

ISSN: 0034-6659

Publication date: 19 June 2019

Abstract

Purpose

Dietary fiber and energy intakes seem to be related to disability and anthropometric indices in multiple sclerosis (MS), a chronic inflammatory disorder of the central nervous system. So, this study was designed to investigate the association between dietary fiber and energy intakes with systemic inflammation, disease severity and anthropometric measurements in MS subjects.

Design/methodology/approach

Four subtypes of 261 MS volunteers were recruited (female = 210, male = 51; mean age 38.9 ± 8.3). A 168-item food frequency questionnaire and nutritionist IV software were used to estimate the amounts of dietary, insoluble, soluble, crude fiber and energy intakes. Serum hs-CRP, extended disability status scale (EDSS), height, weight and Deurenberg equation were also used to evaluate systemic inflammation, disease severity, body mass index (BMI) and percentage body fat, respectively.

Findings

Mean differences among the three hs-CRP and EDSS subgroups for dietary fibers and energy intake were significant (p <0.001). Dietary fiber intake (M = 19.9 ± 4.3 g/day) was a good predictor for EDSS (B = −0.196, p =0.012), and insoluble fiber intake was introduced as the best predictor of hs-CRP (B = −3.293, p <0.001). Energy intake predicted both BMI (B = 0.007, p <0.001) and percentage body fat (B = 0.015, p <0.001).

Originality/value

Hypocaloric and high prebiotic fiber diet may suppress systemic inflammation and thereby modulate disease severity, as well as control anthropometric indices.

Keywords

Citation

Moravejolahkami, A., Paknahad, Z. and Chitsaz, A. (2019), "Dietary intake of energy and fiber in MS patients; an approach to prebiotics role", Nutrition & Food Science , Vol. ahead-of-print No. ahead-of-print. https://doi.org/10.1108/NFS-01-2019-0001

Download as .RIS

Publisher

:

Emerald Publishing Limited

Copyright © 2019, Emerald Publishing Limited

Please note you might not have access to this content

You may be able to access this content by login via Shibboleth, Open Athens or with your Emerald account.
If you would like to contact us about accessing this content, click the button and fill out the form.