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A systematic review and meta-analysis of screening and diagnostic accuracy for hearing loss among under-five children in South-Asian region

Ramesh Athe (Data Science and Intelligent Systems, Indian Institute of Information Technology Dharwad, Dharwad, India and work based at ICMR- Regional Medical Research Centre, Bhubaneswar, India)
Rinshu Dwivedi (Science and Humanities, Indian Institute of Information Technology Tiruchirappalli, Tiruchirappalli, India and work based at ICMR- Regional Medical Research Centre, Bhubaneswar, India)
Krushna Chandra Sahoo (Health Technology Assessment, ICMR- Regional Medical Research Centre, Bhubaneswar, India)
Debdutta Bhattacharya (Department of Microbiology, ICMR- Regional Medical Research Centre, Bhubaneswar, India)
Shalu Jain (Department of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi, India)
Sanghamitra Pati (Department of Public Health, ICMR- Regional Medical Research Centre, Bhubaneswar, India)

International Journal of Human Rights in Healthcare

ISSN: 2056-4902

Article publication date: 13 September 2021

Issue publication date: 2 June 2022

66

Abstract

Purpose

Congenital hearing disabilities among children are associated with lifetime discrepancies in the attainment of speech, poor academic-performance, socio-individual isolation and emotional-maladjustments. The present study aims to combine evidence from randomized, controlled trials to assess the accuracy of hearing-screening procedures and relative diagnostic-tests concomitant with partial/permanent hearing loss (HL) among neonatal and under-five children.

Design/methodology/approach

The steps in this process were conducted according to the PRISMA (Preferred-Reporting-Items-for-Systematic-reviews-and-Meta-Analysis) guidelines. The PubMed, ProQuest, Science-Direct, Cochrane-Library and secondary reference databases were searched. Analyses were carried out by using fixed/random-effects-models for calculating the summary estimates on hearing-screening and test-procedure. Meta-regression-analysis is performed to explore the influence of confounders on the net-pooled effect.

Findings

A total of 1,656 articles were identified, and 1,575 were excluded as they were not relevant to the purpose of the study. Further, out of 81 studies, 67 were excluded with reasons and 14 were included in the final analysis. Three independent reviewers have assessed the titles/abstracts for their potential relevance. The results from meta-analysis indicate that hearing-screening was significantly higher in the intervention group (n 8,102; OR 0.52, 95% CI 0.34, 0.79; p < 0.00001), as depicted via forest plot. Meta-regression analysis indicates a positive relationship between the age and effect size (regression-coefficient 0.638, 95% CI 0.005, 0.731; p < 0.05).

Research limitations/implications

The evidence from the present study can be used as reference for identifying the associated risk indicators, improved hearing-screening and reduction of hearing disability among under-five children.

Practical implications

The results of this review will be used for implementation of a new-born hearing screening, diagnostic accuracy and understanding the risk indicators for HL among under-five children in the South-Asian region. The evidence will be helpful for strategic directions for improved hearing screening and reduction of hearing disability among under-five children.

Social implications

By understanding the underlying dynamics of hearing-screening procedures, hearing-impairments can be identified at an early stage and required treatment can be provided to the children.

Originality/value

The findings of this study indicate that early detection, screening and diagnosis of the HL among the children, especially among the infants and new-born (0–2 years of age), will be of utmost importance in reducing the prevalence of HL, especially among the South-Asian region. This study can be used as a reference for other future studies in the area of hearing-screening, diagnostic accuracy and associated risk indicators among children.

Keywords

Acknowledgements

Acknowledgements

The authors highly acknowledge the encouragement from Health Technology Assessment in India (HTAIn), the Department of Health Research (DHR), Ministry of Health and Family Welfare (MoHFW), Government of India (GoI), New Delhi for carrying out this study and also Indian Council of Medical Research (ICMR), Regional Medical Research Centre (RMRC), Bhubaneswar, India for their insightful inputs.

Declarations: As the present study was based on the secondary data, ethical approval was not required.

Consent for publication: Not applicable.

Availability of data and material: Mentioned datasets used for the current study will be available from the corresponding author on request.

Competing interests: The authors declare that they have no competing interests.

Funding: No funding has been received for the study.

Authors’ contributions: RA and RD developed and piloted the data extraction form and also search strategy for the systematic review and drafted the manuscript. SP supervised the study. RD and RA have written the manuscript with the contribution of KCS. Comments, suggestions and revisions have been done by DB and SJ. All authors reviewed the manuscript and approved the final manuscript.

Citation

Athe, R., Dwivedi, R., Sahoo, K.C., Bhattacharya, D., Jain, S. and Pati, S. (2022), "A systematic review and meta-analysis of screening and diagnostic accuracy for hearing loss among under-five children in South-Asian region", International Journal of Human Rights in Healthcare, Vol. 15 No. 3, pp. 305-317. https://doi.org/10.1108/IJHRH-01-2021-0018

Publisher

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Emerald Publishing Limited

Copyright © 2021, Emerald Publishing Limited

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