Index

Elgar Fleisch (ETH Zurich & University of St. Gallen (HSG), Switzerland)
Christoph Franz (F. Hoffmann-La Roche & University of St. Gallen (HSG), Switzerland)
Andreas Herrmann (University of St. Gallen (HSG), Switzerland)

The Digital Pill: What Everyone Should Know about the Future of Our Healthcare System

ISBN: 978-1-78756-676-7, eISBN: 978-1-78756-675-0

Publication date: 22 March 2021

This content is currently only available as a PDF

Citation

Fleisch, E., Franz, C. and Herrmann, A. (2021), "Index", The Digital Pill: What Everyone Should Know about the Future of Our Healthcare System, Emerald Publishing Limited, Leeds, pp. 197-202. https://doi.org/10.1108/978-1-78756-675-020211020

Publisher

:

Emerald Publishing Limited

Copyright © 2021 Emerald Publishing Limited


INDEX

Adherence
, 95

Aetion Health
, 149

Aggregation
, 160

Akili Interactive Labs
, 90–91

AKL-T01 (project)
, 90

AliveCor
, 53–54

Amazon recommendation system
, 61

American health insurance system
, 11

Amino database
, 126–127

Animation, comic and game style (ACG style)
, 78

Annals of Clinical and Laboratory Research (2017)
, 60

Antibiotics
, 4

Antibodies
, 5

Antidote
, 141–142

Apixio
, 107

Apple
, 55, 103–104, 120, 136, 143–144

Arterys
, 72

Artificial intelligence (AI)
, 43, 71, 82, 99, 109, 138

AI-based IT tools
, 160–161

Atomwise
, 139

Atrial fibrillation (A-fib)
, 53

Attention deficit disorder (ADD)
, 90

Ava
, 56

Ayushman Bharat program
, 9

Azumio
, 56

Babylon Health
, 47–50

Bad cholesterol
, 75

Billing codes
, 122

Biomarkers
, 131

Biovotion
, 56

Blood type system
, 150

Bloomberg news agency
, 11

Buoy Health
, 49

Cardiovascular disease in Mexico
, 22–23

CareMore healthcare chain
, 173

Celcuity
, 151

Cell differentiation
, 104

Century Cures Act
, 148

Chest pain
, 46

Chunyu Yisheng
, 69–70

Citizen scientists
, 61–62

Clinical studies
, 100

digital patient recruitment for
, 140–144

Clinical Trial Transformation Initiative
, 144

Cochrane Crowd platform
, 62

Collaborative robots (cobots)
, 138

Collective Health
, 125–126

Color Genomics
, 57

genetic testing by
, 59–60

Computer processing speed and smart algorithms, continuous improvements in
, 151–152

Computer-aided drug discovery
, 137–140

Computer-assisted methods
, 138

Cyberchondria
, 45–46

Data

collecting, processing, and analyzing
, 106–114

collection
, 106–107

data-driven healthcare networks
, 123–127

digital biomarkers
, 113–114

primary and secondary use of health data
, 111–113

privacy
, 161

problem with distributed incompatible
, 107–109

security
, 114–116

transforming data into medical knowledge
, 109–111

Dexcom
, 56

Diabetes epidemic in China
, 18–22

Diagnostics
, 56–57

Diet
, 22

Digital Adherence Coach
, 95–98

Digital advertising
, 83

Digital assistants
, 169

Digital biomarkers
, 113–114

Digital coach
, 87, 164, 172

Digital doctor–patient relationship
, 63–64

digital one-stop platforms
, 76–77

digital physician assistant
, 70–74

online consultation
, 67–70

online pharmacies
, 74–75

selecting, making appointments with, and reviewing doctors online
, 64–67

unstaffed mini-clinics
, 77–79

Digital drug development
, 135

computer-aided drug discovery
, 137–140

digital patient recruitment for clinical studies
, 140–144

evidence gained from digital RWD
, 144–145

precision medicine
, 149–152

RWD replacing control groups
, 145–149

Digital health data and infrastructure
, 159–162

Digital Healthcare Act
, 94, 148

Digital interventions
, 92

Digital medicine
, 82

Digital one-stop platforms
, 76–77

Digital patient

journey
, 77

recruitment for clinical studies
, 140–144

Digital personal coach
, 85–91

Digital physician assistant
, 70–74

Digital technologies
, 34, 39–41, 119

Digital therapeutics
, 81

characteristics
, 84

Digital Adherence Coach
, 95–98

digital personal coach
, 85–91

by prescription
, 92–95

Digitale-Versorgung-Gesetz (DVG)
, 148

Digitalization
, 25, 39, 57, 63, 121, 136, 156, 168–169, 171

accelerating medical research
, 37–38

boosts efficiency
, 34–35

democratizing medicine
, 35–36

healthy diet and preventive general medicine in Spain
, 32–33

HPB in Singapore
, 31–32

improving quality
, 36–37

individual risk factors
, 27–28

preventive dental medicine in Sweden
, 31

preventive health care in Ancient China
, 30

supports behavioral change
, 34

tomorrow’s medicine
, 33–38

Direct-to-consumer laboratory testing
, 60

DNA strand
, 104

“Do no harm” principle
, 118

Do-it-yourself medicine (DIY medicine)
, 43

citizen scientists
, 61–62

continuous patient self-monitoring
, 53–56

limits
, 60–61

research
, 44–47

response pattern
, 155

self-help and self-diagnosis
, 47–50

sharing between (expert) patients
, 50–52

tests
, 56–61

DocPlanner
, 66–67

Doctor on Demand
, 67–68

Drug

approval
, 146

development process
, 136

discovery process
, 138

Electrocardiogram (ECG)
, 53

Electronic medical records (EMR)
, 102–104

Enlitic
, 71–72

Epigenetic fixation
, 104

Equity
, 119

Ethical challenges
, 118–119

European Commission
, 94

Evidation Health
, 94–95

Exponential growth in data volume
, 105–106

Fast Company
, 54

Fitbit
, 56

Flatiron Health
, 148–149

Freemium business model
, 69

Freenome
, 57

Garmin
, 56

Genes
, 104

Genetic testing by Color Genomics
, 59–60

Genome
, 104

Genomics
, 104

Ginger. io
, 88

GoFundMe crowdfunding platform
, 8–9

Google
, 55, 107, 110–111, 120

Google Flu Trends
, 111

Google Genomics
, 110–111

Google syndrome
, 45–46

Hao Dai Fu platform
, 65

Happify
, 88

Harvard Health Blog
, 45

Healbe
, 56

Health
, 173–175

literacy
, 46–47

Health data
, (see also Real-world data (RWD))

EMR as core of
, 102–104

history
, 101–102

primary and secondary use of
, 111–113

as strategic asset
, 100–106

Health Insurance Portability and Accountability Act (HIPAA)
, 117

Health Promotion Board (HPB)
, 31

in Singapore
, 31–32

Health Tap
, 49

Health Unlocked platform
, 52

Healthcare

costs
, 12–13

expenditure
, 14

systems
, 10, 155, 159, 163, 171

HealthKit
, 56

Healthline
, 45

Healthy 365 App
, 32

“Healthy Choices” program
, 128

Healthy diet
, 32–33

Healthy. io
, 57

Helix
, 57

Hemochromatosis
, 126

Home DNA testing
, 60

Home video industry
, 36

Huawei
, 56

Human Genome
, 150

Human papillomavirus (HPV)
, 135

Hyperactivity
, 90

Hypochondriacs
, 46

IBM Watson
, 142

iCarbonX
, 151–152

ICPerMed consortium
, 165–166

Incentive systems
, 121

Indication
, 146

Infectious diseases
, 29

Infrastructure as a Service (IaaS)
, 110–111

Integrated health systems
, 76

Intervention
, 84

Intestinal iron absorption
, 126

Iron overload
, 126

K Health
, 49

Kaia Health
, 89

Kaia Motion Coach
, 89

Kardia app
, 53

Kardia ECG
, 54

KardiaBand
, 54

KardiaPro system
, 54

Lab robots
, 138

Lead-time bias
, 17

Life expectancy
, 3–4, 16

Lifestyle reward programs
, 127–130

LiveHealth
, 108–109

Longitudinal data
, 105

Luxturna
, 133

Lymphangioleiomyomatosis (LAM)
, 52

Lyra Health
, 88

Magic Leap
, 89–90

Mark2Cure platform
, 62

Mass immunization
, 5

Master patient indices
, 102

Medical ethics
, 118

Medical innovations
, 4

Medical progress
, 3

demographic consequences
, 9–10

economic consequences
, 8–9

ill health
, 6–7

new challenges
, 7

Medical records
, 101

MedicalNewsToday
, 45

Medicare Advantage
, 124

Medicine
, 18

MedScape
, 73–74

Meru Health
, 87–88

Meta-studies
, 92

Microbiome
, 104

Microsoft
, 107

Mindmaze
, 91

Misfit
, 56

Monitoring approach
, 83

Moov
, 56

mPower
, 143

mySugr app
, 86–87

National Institutes of Health (NIH)
, 140

“New Deal on Data”
, 119–120

Next-gen biotech
, 139

Non-communicable diseases (NCDs)
, 6–7, 11, 25, 39, 68, 77, 81, 156, 171

cardiovascular disease in Mexico
, 22–23

chronic
, 19–20

diabetes epidemic in China
, 18–22

human suffering and high costs
, 17–18

prevention
, 47

reduction goals
, 26

NoteSwift
, 107

Novartis
, 120, 139

Nuance
, 107

Off-label use
, 146

Olive
, 107

Omada Health
, 95, 132

Omics
, 102

data
, 104–105

“One-minute Clinic”
, 78

Online consultation
, 67–70

Online pharmacies
, 74–75

Online therapeutics
, 167

Onlinedoctor
, 57

Oscar
, 45

Oscar Health
, 124–125

Ottonova
, 45

Outcome Health
, 45

Outcome-based medicine
, 123

Pathmate Technologies
, 88

Patients
, 155–156

PatientsLikeMe platform
, 50–52

Pay-for-performance models
, 130–133, 168

Payment on delivery
, 167–169

Pear Therapeutics
, 93–94

Penicillin
, 4

Penicillium
, 4

Personalized medicine
, (see Precision medicine)

Petri dish
, 4

PHQ-9 patient questionnaire
, 87

Ping An Good Doctor
, 78

Practice Fusion
, 103

Practo
, 65–66

Pre-Cert program
, 93–94

Precision medicine
, 149–152, 163–166

“Precision Medicine Initiative”
, 150

Preventive dental medicine in Sweden
, 31

Preventive general medicine in Spain
, 32–33

Preventive health care in Ancient China
, 30

Preventive medicine
, 171–175

Privacy or right to informational self-determination
, 116–118

Propeller Health
, 88–89

Proteus Digital Health
, 97–98

Public health infrastructure
, 15–16

Quantified Self movement
, 54–56

Quiagen
, 57

RADLogics
, 72–73

Randomized double-blind studies
, 99

RateMDs
, 67

Re-allocation of roles
, 155–157

Real-world data (RWD)
, 99, 135, 161

allow for time travel
, 145

evidence gained from digital RWD
, 144–145

improving study design’s probability of success
, 146–147

knowledge gained in clinical studies
, 147–149

replacing control groups
, 145–149

uses for existing drugs
, 146

Redox
, 108

ResearchKit platform
, 143

reSET program
, 93

Right to Privacy, The
, 116

Robots
, 138

Roche
, 57, 113–114, 131–132

SageBionetworks
, 143

Samsung
, 56

Sanitas Coach App
, 89

Saykara
, 107

Science 37
, 142–143

Self-learning chatbot
, 48–49

Self-monitoring data
, 105

Siemens
, 57

Sildenafil
, 146

Skepticism
, 5–6

Smallpox
, 4–5

Spain, preventive general medicine in
, 32–33

Spark Therapeutics
, 132–133

State of vulnerability
, 83

Stool sample test by Viome and DayTwo
, 58–59

Sweden, preventive dental medicine in
, 31

Talk-and-tools
, 83–84

TARMED tariff system
, 122

Telemedicine
, 169

TNP-470 molecule
, 138

Transparency
, 167

Triage
, 48

Type 1 diabetes
, 17

Type 2 diabetes
, 17

2 times Andrew Radin (TwoXAR)
, 139–140

23andme
, 57

2Morrow
, 88

uBiome
, 61

UK-based National Institute for Health and Care Excellence
, 130–131

Universal individual privacy
, 116–117

Unstaffed mini-clinics
, 77–79

Urine test by Healthy. io
, 57–58

US Food and Drug Administration (FDA)
, 54, 72, 90, 145

Vaccination
, 5

Vaccines
, 4

Value-based digital compensation systems
, 169

Value-based medicine
, 121, 123

data-driven healthcare networks
, 123–127

lifestyle reward programs
, 127–130

pay for performance
, 130–133

Viome
, 57

Virtual reality (VR)
, 139

Walgreens program
, 128–130

Walmart
, 70

Web-based training
, 83

WebMD
, 45

Weighting factor
, 6

Welfare principle
, 118–119

Westdeutscher Rundfunk
, 147

Withings
, 56

Wlycloud
, 73

World Health Organization (WHO)
, 6, 26, 76, 95, 174

Xiaomi
, 56

Years lost to disability (YLD)
, 6

Your. MD
, 49