Effects of low vitamin D status in rickets and type 1 diabetes in children

D. Papandreou (Aristotle University of Thessaloniki, Thessaloniki, Greece, and School of Medicine, Ahepa General Hospital, Thessaloniki, Greece)
Z. Karabouta (Aristotle University of Thessaloniki, Thessaloniki, Greece, and School of Medicine, Ahepa General Hospital, Thessaloniki, Greece)
I. Rousso (Aristotle University of Thessaloniki, Thessaloniki, Greece, and School of Medicine, Ahepa General Hospital, Thessaloniki, Greece)

Nutrition & Food Science

ISSN: 0034-6659

Publication date: 14 September 2010

Abstract

Purpose

This paper aims to review the metabolism, epidemiology and treatment of vitamin D and calcium insufficiency as well as its relation to rickets and diabetes type 1 during childhood and adolescence.

Design/methodology/approach

The most up‐to‐date and pertinent studies within the literature are included in this narrative review.

Findings

Vitamin D deficiency is common in developing countries and exists in both childhood and adult life. The great importance of vitamin D is the moderation of calcium (Ca) and phosphorus (P) homeostasis as well as the absorption of Ca. While insufficiency of vitamin D is a significant contributing factor to the risk of rickets in childhood, it is possible that a more marginal deficiency of vitamin D during life span contributes to osteoporosis as well as potentially to the development of various other chronic diseases such as diabetes type 1.

Originality/value

This paper gives a concise, up‐to‐date overview to nutritionists and dietitians on how vitamin D deficiency may effect rickets and type 1 diabetes.

Keywords

Citation

Papandreou, D., Karabouta, Z. and Rousso, I. (2010), "Effects of low vitamin D status in rickets and type 1 diabetes in children", Nutrition & Food Science, Vol. 40 No. 5, pp. 447-455. https://doi.org/10.1108/00346651011076956

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Publisher

:

Emerald Group Publishing Limited

Copyright © 2010, Emerald Group Publishing Limited

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