TY - CHAP AB - Purpose – This chapter addresses the nature, formalization, and neural bases of (affective) social ties and discusses the relevance of ties for health economics. A social tie is defined as an affective weight attached by an individual to the well-being of another individual (‘utility interdependence’). Ties can be positive or negative, and symmetric or asymmetric between individuals. Characteristic of a social tie, as conceived of here, is that it develops over time under the influence of interaction, in contrast with a trait like altruism. Moreover, a tie is not related to strategic behavior such as reputation formation but seen as generated by affective responses.Methodology/approach – A formalization is presented together with some supportive evidence from behavioral experiments. This is followed by a discussion of related psychological constructs and the presentation of suggestive existing neural findings. To help prepare the grounds for a model-based neural analysis some speculations on the neural networks involved are provided, together with suggestions for future research.Findings – Social ties are not only found to be important from an economic viewpoint, it is also shown that they can be modeled and related to neural substrates.Originality/value of the chapter – By providing an overview of the economic research on social ties and connecting it with the broader behavioral and neuroeconomics literature, the chapter may contribute to the development of a neuroeconomics of social ties. VL - 20 SN - 978-1-84855-304-0, 978-1-84855-305-7/0731-2199 DO - 10.1016/S0731-2199(08)20006-3 UR - https://doi.org/10.1016/S0731-2199(08)20006-3 AU - van Winden Frans AU - Stallen Mirre AU - Ridderinkhof K. Richard ED - Daniel Houser ED - Kevin McCabe PY - 2008 Y1 - 2008/01/01 TI - On the nature, modeling, and neural bases of social ties T2 - Neuroeconomics T3 - Advances in Health Economics and Health Services Research PB - Emerald Group Publishing Limited SP - 125 EP - 159 Y2 - 2024/05/09 ER -